Train Your Brain Fitness SC: Exercise for Cognitive Impairments

This study, called "Train Your Brain Fitness SC," is testing an exercise and coaching program for adults in South Carolina who have mild to moderate cognitive impairment. The program involves supervised exercise and behavior modification support, aiming for 60 minutes of moderate intensity exercise twice a week. This includes cardiovascular activity and functional strength training. The main goal is to see if the program is practical to run, if people enjoy it, and if it helps improve endurance, mobility, and cognitive function over 3, 6, 9, and 12 months. You might be able to join if you are an adult with a medical diagnosis of mild-moderate cognitive impairment, have medical clearance for exercise, and can follow two-step commands. The study plans to enroll 50 participants.

Study design
This is an interventional study, meaning participants will receive a specific intervention. It aims to enroll 50 participants.
What's involved
Participants will attend exercise sessions twice a week. These sessions will involve endurance, strength, balance, and mobility training, with coaches providing plans and monitoring progress.
Compensation
Not stated in the trial record.
Follow-up
Changes in endurance, mobility, and cognitive function will be measured at 3, 6, 9, and 12 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06799429

Train Your Brain Fitness SC: An Exercise Intervention for People With Cognitive Impairments

Recruiting
NAAges 18+InterventionalSupportive care
University of South Carolina
~50 participants
Updated 2026-06-01 on ClinicalTrials.gov
What's tested:Supervised Exercise and Behavior Modification SupportMonitored Exercise and Behavioral Modification Support

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Aim 1 Feasibility: Recruitment and Uptake through qualified referrals
Measured over through study completion, an average of 1 year
+7 more outcomes measured
Mild-moderate Cognitive Impairment

NCT06799429

Where you'd take part

This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Arnold School of Public Health

    Columbia, South Carolinastudy coordinator listed

    Recruiting

  • Sumter YMCA

    Sumter, South Carolinastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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Eligibility criteria

Inclusion

adult (age \>18)
medical diagnosis of mild-moderate cognitive impairment
medical clearance by referring provider for exercise
able to follow 2-step commands

Exclusion

significant pain with movement (\>5/10)
severe balance impairments or lack of independence on and off exercise equipment (by physical therapist judgment at Intake)
  • Aim 1 Feasibility: Recruitment and Uptake through qualified referralsthrough study completion, an average of 1 year

    percent of qualified referrals beginning the program

  • Aim 1 Feasibility: Program Fidelity Dosage: session adherencethrough study completion, an average of 1 year

    mean percentage adherence (number of sessions completed / number of sessions scheduled)

  • Aim 1 Feasibility: Program Fidelity Dosage: Session Durationthrough study completion, an average of 1 year

    mean percentage duration

  • Aim 1 Feasibility: Program Fidelity: Exercise Intensitythrough study completion, an average of 1 year

    mean percent of time spent in target heart rate zone of 60-85% of age predicted maximum

  • Aim 1 Feasibility: Acceptability: Participant Satisfactionthrough study completion, an average of 1 year

    mean of 5 point likert scale 1-not satisfied to 5-extremely satisfied

  • Aim 2 Exploratory Individual Outcomes: Processing Speed and Executive Function through the Oral Symbol Digits Test (NIH Toolbox)pre-program (baseline), 3, 6 9 and 12 months

    Score is number of correct responses (0-144), with higher score as better performance

  • Aim 2 Exploratory Individual Outcomes: Cardiovascular Endurance through the six-minute walk testpre-program (baseline), 3, 6 9 and 12 months

    Score is meters walked, higher is better performance

  • Aim 2 Exploratory Individual Outcomes: Working Memory through the Auditory Verbal Learning Test (NIH Toolbox)pre-program (baseline), 3, 6 9 and 12 months

    Score is number of correct responses (0-45), with higher score as better performance