Smart Underwear to Measure Diet-Induced Hydrogen Sulfide Production
This study is testing a new "Smart Underwear" device that measures hydrogen sulfide (H₂S) in your gut. H₂S is a gas produced by the bacteria in your gut, and too much of it might be linked to health problems like colon cancer. Researchers want to see if this wearable device can accurately measure how your diet changes H₂S levels. You would eat two different healthy diets, one high in cysteine (a building block of protein) and one low in cysteine, for six days each. The goal is to find a better way to measure H₂S production, which could help us understand its role in health and disease. They are looking for about 25 generally healthy adults, aged 18 and older, to participate.
- Study design
- This is a single-site study where participants will try two different diets in a random order. About 25 healthy volunteers will be enrolled.
- What's involved
- You would follow a high cysteine diet for 6 days and a low cysteine diet for 6 days, with about an 11-day break in between. The Smart Underwear device would measure H₂S daily during these diet periods.
- Compensation
- Not stated in the trial record.
- Follow-up
- Measurements of hydrogen sulfide will be taken daily for 6 days during each dietary intervention period, for a total of 12 days.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Smart Underwear to Measure Diet-Induced Hydrogen Sulfide Production
At a glance
Conditions
NCT06802276
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University of Colorado Anschutz Medical Campus
Aurora, Coloradostudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Noel T Mueller, PhD · PRINCIPAL_INVESTIGATOR · University of Colorado, Denver
- Andrew B Hall, PhD · PRINCIPAL_INVESTIGATOR · University of Maryland, College Park
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
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Inclusion
Exclusion
What this trial measures
- Hydrogen sulfide (H2S)Daily for 6 days during each dietary intervention period (total of 12 days).
Participants will be instructed to wear the Smart Underwear device for all waking hours during the baseline and feeding periods except for bathing and exercise. The Smart Underwear device does not need to be worn while sleeping due to the decreased frequency of flatus. Participants will be warned by the Smart Underwear device if the device is not worn for at least 12 hours per day or if the device detects that it is being worn incorrectly. Aggregate metrics from the device will be included in either the on-site or virtual discussions with staff.