Observational Study on Aspirin Metabolism and Preeclampsia Risk
This study is looking at the relationship between how your body processes aspirin and certain markers of metabolic health if you are pregnant and at risk for preeclampsia (a serious blood pressure condition during pregnancy). Researchers want to understand this connection better. You may be able to join if you are between 18 and 45 years old, pregnant, and your doctor has recommended aspirin to prevent preeclampsia. The study will measure specific substances in your body, like Hexadecadienoate and Salicylate (a component of aspirin), about an hour after you drink a sugary solution during a single visit between 14 and 20 weeks of pregnancy. The current status of this study is unclear, and it aims to include 50 participants.
- Study design
- This is an observational study, meaning researchers will collect information without giving you a specific treatment. It plans to enroll 50 pregnant individuals.
- What's involved
- You would undergo a 2-hour oral glucose tolerance test (OGTT) for blood and urine collection, along with surveys, body composition measurements, and other assessments during a single study visit.
- Compensation
- Not stated in the trial record.
- Follow-up
- Measurements for the primary endpoints are taken at 60 minutes after glucose ingestion during a single study visit between 14-20 weeks gestational age.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Inclusion
Exclusion
What this trial measures
- Hexadecadienoate (z score)60 minutes after ingestion of 75 grams of glucose during a single study visit between 14-20 weeks gestational age
Hexadecadienoate (long chain poly unsaturated fatty acid metabolite obtained from metabolomics assay) (z score)
- Salicylate (z score)60 minutes after ingestion of 75 grams of glucose during a single study visit between 14-20 weeks gestational age
Salicylate (benzoate metabolite obtained from metabolomics assay)(z score)