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NCT06804551

Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain

Enrolling by Invitation
NAAges 18+InterventionalTreatment
University of Kansas Medical Center
~30 participants
Updated 2026-03-11 on ClinicalTrials.gov
What's tested:iovera systemRadiofrequency ablation alone

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Confirm the feasibility of a double-blinded protocol
Measured over After the last End of Study Visit

Conditions

Chronic Low-back Pain

Explore related trials

Chronic low back pain

Where it's being run

1 sites across 1 states
Kansas1

Study leadership

  • Neil A Segal, MS, MD · PRINCIPAL_INVESTIGATOR · University of Kansas Medical Center

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Subjects at least 18 years of age at Screening
Chronic low back pain (≥ 3 months)
Successful trial of two diagnostic medial branch blocks
Failure of at least three months of conservative non-operative therapy (e.g., physical therapy, chiropractic care, sleep hygiene, weight loss, spinal injections, NSAIDs, physician-directed exercise program or other appropriate pain medicine)
Able to provide informed consent, adhere to the study visit schedule, and complete all study assessments

Exclusion

Active workers' compensation, personal injury, Social Security disability insurance (SSDI), or other litigation/compensation related to the spine
Infection in the back or open wounds in the back
Cancer
Fractures in the back
Pain shooting down the leg
Pain when walking up/downhill
Any back surgery or metal objects in the back
Any implants of any kind in the body
Currently pregnant, nursing, or planning to become pregnant during the study
Blood clots
History of RFA treatment in back
Drug abuse

What this trial measures

  • Confirm the feasibility of a double-blinded protocolAfter the last End of Study Visit

    At the end of the study, all of the study team members will fill out a structured questionnaire to determine the feasibility. This questionnaire will include the following: 1. Considering you role in this study, is it feasible to continue to an efficacy Randomized Control Trial applying the same protocols and procedures used in the current pilot study without modifications? 2. If not, considering you role in this study, is it feasible to continue to an efficacy Randomized Control Trial applying modifications to the protocols and procedures used in the current pilot study? As the aim of this pilot study is not to assess effectiveness or efficacy, formal hypothesis testing will not be determined.