Observational Study of Flu Infection at UPHS

This study, called "Flu Infection at UPHS," is looking at how your body's immune system responds to the influenza virus (the flu). Researchers want to understand if your body mostly uses existing immune memory or creates new immune responses when you get the flu. You might be able to join if you are 18 or older and have recently tested positive for the flu within the University of Pennsylvania Health System. The main goal is to see how flu infection affects your neutralizing antibody titers (a measure of your immune protection) against different flu strains over two years. The study plans to enroll up to 50 participants each year. The current recruitment status is unclear.

Study design
This is an observational study, meaning researchers will watch and collect information without giving you a specific treatment. It plans to enroll up to 50 participants each year.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for two years to measure the effect of influenza virus infection on neutralizing antibody titers.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06807840

Flu Infection at UPHS

Recruiting
Not specifiedAges 18+Observational
University of Pennsylvania
~50 participants
Updated 2026-06-03 on ClinicalTrials.gov
What's tested:influenza virus infection

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Effect of influenza virus infection on neutralizing antibody titers to contemporary and historical influenza virus strains
Measured over 2 years
Influenza Human
1 sites across 1 states
Pennsylvania1

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  • Effect of influenza virus infection on neutralizing antibody titers to contemporary and historical influenza virus strains2 years

    The investigators will compare neutralizing antibodies in sera, plasma, and nasal swab samples against the influenza strain that each participant is infected with as well as historical and recently circulating influenza virus strains. Antibody titers between different strains will be compared to understand if memory or de novo immune responses are generated following influenza infection based on inferred influenza exposure history.