This study is looking at how a nutritional ketone supplement called Kenetik affects brain function and alcohol consumption in people with Alcohol Use Disorder. Researchers want to see if Kenetik changes how your brain uses energy and how much alcohol you might drink. You would receive Kenetik and a placebo (a drink that looks and tastes the same but has no active ingredient) at different times. The study will measure brain energy using MRI (magnetic resonance imaging, which uses magnets and radio waves to create detailed images of your brain) and FDG PET/CT scans (which use a small amount of a radioactive tracer to show how your brain and tissues are working). Researchers will also observe alcohol consumption in a special "alcohol bar lab." The study aims to enroll 60 participants aged 21-65 who have mild to moderate Alcohol Use Disorder and are not currently seeking treatment.

Study design

This is a randomized, double-blind, crossover study involving 60 participants. This means participants will randomly receive either Kenetik or a placebo, and neither you nor the researchers will know which you are receiving at the time.

What's involved

You would undergo two MRI scans, two FDG PET/CT scans, and two alcohol bar lab visits. At each of these visits, you would receive either Kenetik or a placebo beverage.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoints for brain energetics are measured at 90 minutes after receiving the supplement. The overall follow-up duration is not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.