TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD

This study, called TURN-IT FOG, is looking at two different rehabilitation programs to help people with Parkinson's disease (PD) who experience Freezing of Gait (FOG). FOG is when you suddenly feel like your feet are stuck to the ground when you try to walk. The study wants to see if a turning-focused agility exercise or a strength-based exercise can reduce FOG and improve daily movement. Researchers will measure FOG severity based on what patients say, what clinicians observe, and data from wearable sensors. You might be able to join if you are 50 to 80 years old, have been diagnosed with PD by a movement disorders neurologist, and experience FOG. The study aims to see if these interventions are effective enough to warrant a larger clinical trial in the future. The current recruitment status is unclear.

Study design
This interventional study plans to enroll 60 participants. You will be randomly assigned to one of two intervention groups.
What's involved
You will have one-on-one training sessions three times a week for 6 weeks. You will also complete assessments before and after the intervention and use wearable sensors daily.
Compensation
Not stated in the trial record.
Follow-up
Your Freezing of Gait severity will be measured from enrollment through the 8-week intervention period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06815302

TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD

Recruiting
NAAges 50–80InterventionalTreatment
Oregon Health and Science University
~60 participants
Updated 2025-07-28 on ClinicalTrials.gov
What's tested:Experimental interventionActive intervention

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Patient- Perceived Freezing of Gait Severity
Measured over From enrollment/randomization through intervention; 8 weeks
+2 more outcomes measured
Parkinson Disease
Freezing of Gait Symptoms in Parkinson Disease

NCT06815302

Where you'd take part

This study runs at 3 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Arizona State University

    Tempe, Arizonano site contact published

    Recruiting

  • Oregon Health and Science University

    Portland, Oregonno site contact published

    Recruiting

  • University of São Paulo, Bauru Campus

    Bauru, São Paulo, Brazilno site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Martina Mancini, PhD · PRINCIPAL_INVESTIGATOR · Oregon Health and Science University

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Eligibility criteria

Inclusion

diagnosis of idiopathic PD from movement disorders neurologist with the United Kingdom Brain Bank criteria of bradykinesia with one or more of the following - rest tremor, rigidity, and balance problems not from visual, vestibular, cerebellar or proprioceptive conditions
reporting FOG in the New Freezing of Gait questionnaire (N-FOGQ)
Hoehn \& Yahr stages II-IV
ages 50-80 years old
cognitive ability sufficient to participate in testing procedures and exercise classes
be willing and able to participate in exercise intervention 3x/week for 6 weeks

Exclusion

Major musculoskeletal or neurological disorders, structural brain disease, epilepsy, acute illness or health history, other than PD, significantly affecting gait and turning (i.e., musculoskeletal disorder, vestibular problem, head injury, stroke, cardiac disease)
medical condition or medications that precludes moderate-intensity exercise
Montreal Cognitive Assessment (MoCA) ≤21 or inability to follow directions
excessive use of alcohol or recreational drugs
recent change in medication
inability to stand and walk for 2 minutes without an assistive device
  • Patient- Perceived Freezing of Gait SeverityFrom enrollment/randomization through intervention; 8 weeks

    Change in freezing of gait severity with the intervention (scored in likert scale by the patient; 3 = Much improved, 2 = Somewhat improved, 1 = Minimally improved, 0 = No change, -1 = Minimally worse, -2 = Somewhat worse, -3 = Much worse)

  • Clinician- Perceived Freezing of Gait SeverityFrom enrollment/randomization through intervention; 8 weeks

    Change in freezing of gait severity with the intervention (scored in likert scale by the clinician; 3 = Much improved, 2 = Somewhat improved, 1 = Minimally improved, 0 = No change, -1 = Minimally worse, -2 = Somewhat worse, -3 = Much worse

  • Sensors-based Freezing of gait severityFrom enrollment/randomization through intervention; 8 weeks

    Freezing of Gait Index calculated during a 360 degrees turning in place from wearable sensors; continuous scale, with a higher positive score meaning a greater level of freezing of gait.