This study is looking into whether ginger root extract can help people with chronic sciatic pain. Sciatic pain is a type of neuropathic pain (nerve pain) that affects many people. Researchers want to understand how ginger might work through the connection between the gut and the brain to reduce this pain. You would receive either ginger root extract or a placebo (an inactive substance like starch) daily for 8 weeks. To join, you need to be between 18 and 85 years old, have chronic sciatic pain for at least 3 months, and have a pain level of more than 3 out of 10. The study aims to see if ginger can reduce pain, measured by a pain inventory, and also to look at certain markers in your blood and stool related to gut health.

Study design

This is a randomized, double-blinded, and placebo-controlled study with 80 participants. Participants will be randomly assigned to receive either ginger or a placebo.

What's involved

You would take either ginger root extract or a placebo daily for 8 weeks. Measurements of blood, stool, and pain levels will be taken at the beginning and after 8 weeks.

Compensation

Not stated in the trial record.

Follow-up

Your progress will be measured at the start of the study and again after 8 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.