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Post-Operative Steroids After Sleep Surgery for Obstructive Sleep Apnea

This study is looking at whether a medication called dexamethasone, a type of steroid, can help reduce pain after sleep surgery for Obstructive Sleep Apnea (OSA). OSA is a condition where breathing stops and starts during sleep. Researchers want to see if dexamethasone improves pain, helps you eat a regular diet sooner, and reduces the need for narcotic pain medication after surgery. You could be eligible if you are an adult aged 18 or older, having certain types of sleep surgery, and can complete study questions in English. The study will measure pain levels two weeks after surgery to see if the treatment is successful. The current status of this study is unclear.

Study design
This is a randomized, placebo-controlled, double-blind study, meaning participants will be randomly assigned to receive either dexamethasone or a placebo, and neither you nor your doctors will know which you are receiving. The study plans to enroll 120 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your pain control will be measured at 2 weeks after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06818981

Post-Operative Steroids After Sleep Surgery

Not Yet Recruiting
PHASE2Ages 18+InterventionalSupportive care
Medical University of South Carolina
~120 participants
Updated 2026-05-06 on ClinicalTrials.gov
What's tested:8mg dexamethasone

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Pain control
Measured over 2 weeks

Conditions

Obstructive Sleep Apnea

Explore related trials

Obstructive Sleep Apnea

Where it's being run

1 sites across 1 states
South Carolina1

Study leadership

  • Nicolas Poupore · PRINCIPAL_INVESTIGATOR · Medical University of South Carolina

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adults 18 years or older
Undergoing sleep surgery, specifically palatopharyngoplasty, tonsillectomy with or without adenoidectomy, uvulectomy, hypoglossal nerve stimulation, genioglossal advancement, or maxillomandibular advancement
Ability to complete all study questions in English

Exclusion

Any self-reported allergies to corticosteroids
Intra-operative surgical or anesthetic complication
Pre-operative steroid use (defined as any steroid use greater than three days duration within 30 days prior to sleep surgery)
Inability to perform study due to underlying medical condition
Inability to answer postoperative questionnaires due to underlying medical conditions

What this trial measures

  • Pain control2 weeks

    As determined by a validated visual analog scale, with scores being scaled from 0 to 10, with 0 being the lowest score (no pain) and 10 being the highest score (most extreme amount of pain)