Unidos Contra el VPH: Comparing Cervical Cancer Screening Methods

The Unidos Contra el VPH study is looking for easier ways to screen for cervical cancer, especially for people who find traditional Pap tests difficult. This study compares three different screening methods: self-sampling with urine, self-sampling with a swab, and the standard in-clinic Pap/HPV co-testing. The goal is to see which method helps more people complete their cervical cancer screening. You may be able to join if you are a woman with a cervix, aged 30 to 65, and haven't had a Pap test in at least three years. You cannot join if you've had a hysterectomy or a personal history of cervical cancer. The study aims to enroll 735 participants.

Study design
This interventional study plans to enroll 735 women to compare three different cervical cancer screening methods.
What's involved
You would participate in one of three cervical cancer screening methods: self-sampling with urine, self-sampling with a swab, or an in-clinic Pap/HPV co-test.
Compensation
Not stated in the trial record.
Follow-up
Completion rates will be measured within 60 days of enrollment.

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NCT06825689

Unidos Contra el VPH

Recruiting
NAAges 30–65InterventionalScreening
University of Texas at Austin
~735 participants
Updated 2026-06-10 on ClinicalTrials.gov
What's tested:Self-sampling with urineSelf-sampling with swabIn-clinic Pap/HPV co-testing

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Comparison of Completion Rates Among Three Cervical Cancer Screening Methods
Measured over Screening completion within 60 days of enrollment
Human Papilloma Virus (HPV)
Cervical Cancers
1 sites across 1 states
Texas1

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Eligibility criteria

Inclusion

Individuals with a cervix who are 30-65 years and have not undergone a Pap test in at least three years.

Exclusion

Having had a hysterectomy or a personal history of cervical cancer.
  • Comparison of Completion Rates Among Three Cervical Cancer Screening MethodsScreening completion within 60 days of enrollment

    This study will compare the effectiveness of three cervical cancer screening methods in achieving screening completion. Participants will be randomized to one of the following groups: In-home HPV self-sampling using a urine sample In-home HPV self-sampling using a cervico-vaginal swab In-clinic cervical cancer screening via clinician-collected HPV and Pap test The primary outcome will be the screening completion rate-- the proportion of participants who successfully complete their assigned screening method within the study period.