Adaptive Interventions for Emergency Department Patients With Opioid Use Disorder

This study is looking at different ways to help adults with opioid use disorder (OUD) who come to the emergency department. It tests several approaches, including a Substance Use Navigator (SUN) to help you start buprenorphine treatment and connect you to follow-up care. Another option is SUN plus TeleBridge, which offers an immediate video call with a buprenorphine provider. If you don't respond well to the first treatment, you might receive additional support from an ED-based team, possibly with extra behavioral health support. The main goal is to see which of these methods helps people fill their buprenorphine prescriptions for the longest time over six months. You can join if you are 18 or older, have a probable OUD diagnosis, and speak English or Spanish. The study plans to enroll 500 people, but its current status is unclear.

Study design
This is a two-stage, randomized study involving about 500 participants. It aims to find the most effective way to help people with opioid use disorder.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for six months after joining the study to track how often they fill their buprenorphine prescriptions.

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NCT06827288

Adaptive Interventions for Emergency Department Patients With Opioid Use Disorder

Recruiting
NAAges 18+InterventionalHealth services
RAND
~500 participants
Updated 2026-02-19 on ClinicalTrials.gov
What's tested:SUNSUN + TelebridgeED-ITTED-ITT + BHS

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
The number of days a buprenorphine prescription was filled in the 6 months after enrollment
Measured over 6 months from date of enrollment
Opioid Use Disorder
1 sites across 1 states
California1

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Eligibility criteria

Inclusion

Presented for ED care at ARMC
Age 18 or older
Probable OUD diagnosis
Speak and understand English or Spanish
Have capacity to give informed consent
Provide a signed and dated informed consent form
  • The number of days a buprenorphine prescription was filled in the 6 months after enrollment6 months from date of enrollment