Dietary Wild Blueberries and Joint Health Study

This study is looking at how eating wild blueberries might affect your gut health, inflammation (swelling in the body), and joint function. We're testing if 25 grams of freeze-dried wild blueberry powder each day, compared to a placebo (an inactive powder), can improve these areas over 12 weeks. You might be able to join if you are between 40 and 75 years old and have documented arthritis in multiple joints or your knee. We'll measure changes in your joint function through blood tests after 12 weeks to see if the blueberries have an effect. The current recruitment status is unclear.

Study design
This interventional study plans to enroll 50 participants. It compares freeze-dried wild blueberry powder to a placebo powder.
What's involved
Participants will consume either 25g of freeze-dried wild blueberry powder or a matched placebo powder daily for 12 weeks, with a 2-week break (washout phase) between treatments.
Compensation
Not stated in the trial record.
Follow-up
Serum biomarkers of joint function will be measured at 12 weeks.

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NCT06828159

Dietary Wild Blueberries and Joint Health

Recruiting
NAAges 40–75Interventional
University of Nevada, Las Vegas
~50 participants
Updated 2025-11-05 on ClinicalTrials.gov
What's tested:Wild blueberryPlacebo

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Serum biomarkers of joint function
Measured over 12 weeks
Gut -Microbiota
Inflammation Biomarkers
Pain Assessment
Joint Pain
1 sites across 1 states
Oklahoma1

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Eligibility criteria

Inclusion

Adults with documented multi-joint/knee arthritis

Exclusion

inability to give informed consent
pregnancy or lactation
planned knee replacement surgery
allergy or contraindication to berries
recent trauma of the knee responsible of the symptomatic knee
intra-articular injection in the target knee/hip in the last 3 months
oral corticosteroid therapy ≥ 5 mg/day (prednisone equivalent) at baseline
use of berry extracts in the last 3 months
special diets
cancer treatment
bone diseases
  • Serum biomarkers of joint function12 weeks

    Serum biomarkers of inflammation and cartilage degradation will be measured in the wild blueberry and placebo groups and compared for outcomes. Pain scores will also be measured using self-reported questionnaires.