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Comparing Surgical Techniques for Testicular Cancer

This study is looking at two ways to perform surgery for suspected testicular cancer, called radical orchiectomy (removal of the testicle). One method involves cutting a tissue layer called the external oblique fascia, which is the standard approach. The other method tries to avoid cutting this fascia. Researchers want to see if sparing the external oblique fascia can reduce your pain after surgery, how much pain medication you might need, if you experience nerve pain, and if there are differences in complications. You may be able to join if you are a man over 18, are having surgery for suspected testicular cancer, and are not currently taking opioid pain medication for another reason. The study aims to enroll 80 participants.

Study design
This interventional study compares two surgical techniques in 80 men. It is not specified if participants will be randomly assigned to a technique.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your pain level will be measured daily from the day of surgery through seven days after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06828185

Patient Reported Experiences With Sparing External Oblique Fascia Vs Standard Inguinal Orchiectomy

Recruiting
NAAges 18+Interventional
Loma Linda University
~80 participants
Updated 2026-07-10 on ClinicalTrials.gov
What's tested:Radical inguinal orchiectomyRadical external oblique fascia sparing orchiectomy

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Postoperative Pain Level
Measured over Change between Postoperative day 0 [the day surgery was completed] through postoperative day 7

Conditions

Testicular Cancer

Explore related trials

Malignant Testicular Neoplasm

Where it's being run

1 sites across 1 states
California1

Who to contact

Muhannad Alsyouf, MD
[email protected]
9095584000 · ext. 44196
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Participants undergoing radical orchiectomy for suspected testicular malignancy
Testicular malignancy can be germ cell tumor or non germ cell tumors, including paratesticular tumors as long as a radical orchiectomy is planned
Participants over 18 years of age who can provide informed consent
Participants not currently using opiates for another reason
Regional and metastatic patients are allowed, as long as participant does not require opiates for pain related to metastatic disease
No contraindication for participant to receive standardized medication pathway in the peri-operative period.

Exclusion

Clinical T4 disease
History of illicit substance abuse (including prior opioid abuse) except for marijuana
Participants who underwent chemotherapy or radiotherapy prior to orchiectomy
Opioid use within 1 month of study enrollment
Participants with large testis masses requiring skin incision larger than 8 cm in size.
Participants with large testis masses requiring orchiectomy through an incision other than the standard transverse inguinal incision (i.e. hockey stick incision, vertical incision)

What this trial measures

  • Postoperative Pain LevelChange between Postoperative day 0 [the day surgery was completed] through postoperative day 7

    Post-operative pain levels will be measured by the Short Form Inguinal Pain Score (sf-IPQ) The score range is between 0 and 12, with zero points indicating no pain and 12 points indicating the most intense pain. Scores for subjects undergoing inguinal orchiectomy will be compared to subjects undergoing external oblique fascia sparing radical orchiectomy.