This study is looking at different washes applied after the first cut in shoulder replacement surgery to see if they can lower the amount of *C. Acnes* bacteria. *C. Acnes* is a common skin bacteria that can sometimes cause infections. You could be in one of four groups: receiving Xperience Antimicrobial Wash, 3% hydrogen peroxide, 10% povidone-iodine (Betadine), or no wash after the initial incision. Researchers will take bacterial cultures to see if these washes reduce *C. Acnes*. To join, you must be at least 18 years old, need a primary shoulder replacement, and have tried at least 6 weeks of other treatments. The study aims to see if these washes lead to fewer positive *C. Acnes* cultures up to 18 days after surgery. The current recruitment status is unclear.

Study design

This is a randomized controlled trial with 150 participants, meaning you would be randomly assigned to one of four groups. The study is interventional, testing different washes.

What's involved

You will undergo shoulder replacement surgery. Bacterial cultures will be taken from your skin, incision site, shoulder joint, and the room air. You will also have follow-up clinic visits for wound healing and complications at 2 weeks, 6 weeks, 3 months, 6 months, and 1 year after surgery.

Compensation

Not stated in the trial record.

Follow-up

You will be followed for wound healing and complications for up to 1 year after your surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.