An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant
{ "Study of VX-880 for Type 1 Diabetes with a Kidney Transplant", "This study is looking at a treatment called VX-880 for people who have Type 1 Diabetes (T1D) and have also had a kidney transplant. VX-880 is given by infusion into a vein in the liver. The main goal is to see if VX-880 can help participants become independent of insulin one year after receiving the treatment. Researchers will also check how safe VX-880 is and how well people tolerate it. You might be able to join if you are between 18 and 65 years old, have had T1D for at least 5 years and rely on insulin, and are on a stable regimen of certain immunosuppression medicines (like tacrolimus and mycophenolate). The study plans to enroll 10 participants, but its current status is unclear.", "design": "This is an interventional study, meaning participants will receive a specific treatment. It aims to enroll 10 participants.", "commitments": "You would need to have a clinical history of Type 1 Diabetes with at least 5 years of insulin dependence and be on a stable immunosuppression regimen for at least 4 weeks. You would also need to use a continuous glucose monitor (CGM) for at least 4 weeks before screening and be willing to use it throughout the study.", "compensation": "Not stated in the trial record.", "follow_up": "The primary outcome is measured at 1 year after the VX-880 infusion, suggesting follow-up for at least that long.", }
- Study design
- Not specified.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant
At a glance
Conditions
Where it's being run
7 sites across 4 statesWho to contact
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Inclusion
Exclusion
What this trial measures
- Proportion of Participants who are Insulin IndependentAt 1 year After VX-880 infusion