Observational Study on Bite Force and Dental Pain
This study is looking at how dental pain, specifically from conditions like irreversible pulpitis (inflammation of the tooth's nerve), apical periodontitis (inflammation around the tooth's root), and pulpal necrosis (death of the tooth's nerve), affects bite force. Researchers want to understand if certain pain mechanisms, like mechanical allodynia (pain from normally non-painful touch) and central sensitization (when your nervous system becomes over-sensitive to pain), play a role. The goal is to see if these mechanisms can be targets for new pain treatments, potentially reducing the need for opioids. You might be able to join if you are between 18 and 89 years old and are getting a filling or root canal on a lower molar tooth. The study aims to measure mechanical allodynia and central sensitization to understand how dental pain works. The current recruitment status is unclear.
- Study design
- This is an observational study planning to enroll 112 participants. It is not specified if it is randomized, blinded, or what phase it is.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The study measures mechanical allodynia at baseline and 10 minutes after local anesthesia, and central sensitization at baseline.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Bite Force Measurements
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Varvara Vanessa Chrepa, DDS, MS, PhD · PRINCIPAL_INVESTIGATOR · Rutgers School of Dental Medicine
- Gayathri Subramanian, PhD, DMD · PRINCIPAL_INVESTIGATOR · Rutgers School of Dental Medicine
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Mechanical AllodyniaBaseline
Ipsilateral full arch and tooth specific bite-force
- Mechanical Allodynia10 minutes post-local anesthesia
Ipsilateral full arch and tooth specific bite-force
- Central SensitizationBaseline
Contralateral tooth specific bite-force
- Central Sensitization10 minutes post-local anesthesia
Contralateral tooth specific bite-force