Cervical Cancer Screening with HR-HPV Testing and Self-sampling

This study aims to improve cervical cancer screening in underserved communities by looking at a new approach called primary HR-HPV testing with self-sampling. HR-HPV testing checks for the human papillomavirus (HPV) that can cause cervical cancer. The study wants to understand how healthcare providers, staff, and patients feel about using self-sampling for these tests. The goal is to increase the number of people getting screened for cervical cancer and to make sure those with abnormal results get the follow-up care they need. You may be able to join if you are a woman between 18 and 65 years old and are eligible for cervical cancer screening. The study hopes to increase screening rates by 10% and improve awareness of this new testing method.

Study design
This is an interventional study with a planned enrollment of 7100 participants. It involves different groups, including patients, healthcare providers, and community members.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Safety and adverse events will be monitored through study completion, which is an average of 1 year.

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NCT06843720

Expanding Access to Cervical Cancer Screening Through Primary HR-HPV Testing and Self-sampling: a Multicomponent Intervention for Safety Net Health Systems

Recruiting
NAAges 18–65InterventionalScreening
M.D. Anderson Cancer Center
~7,100 participants
Updated 2026-06-23 on ClinicalTrials.gov
What's tested:HR-HPV Testing

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Safety and Adverse Events (AEs). Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 4.03
Measured over Through study completion; an average of 1 year.
HR-HPV Testing
1 sites across 1 states
Texas1

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Eligibility criteria

Inclusion

Currently a resident in the state of Texas
Attend for care at a partner clinic enrolled in the study
Women and persons with a cervix
Age 25-65
Due or past due for cervical cancer screening
Employed at least part-time by a partnering health system
Age 18+
Participate in at least one Project ECHO session
Age 18+
Participate in at least one clinical network session
Age 18+

Exclusion

Report being currently pregnant
History of total hysterectomy
History of cervical cancer
  • Safety and Adverse Events (AEs). Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 4.03Through study completion; an average of 1 year.