Study of Plasma PD-L1 Testing in Lung Cancer Immunotherapy

This study is looking at how levels of PD-L1 (a protein that can help cancer cells hide from the immune system) in your blood change during immunotherapy for lung cancer. It uses a special blood test called Circulogene liquid biopsy testing to measure PD-L1 and other markers. You may be able to join if you have stage IV or inoperable stage IIIB non-small cell lung cancer (NSCLC) and are starting treatment with an anti-PD-1/L1 immunotherapy, such as a monoclonal antibody. The study aims to see if changes in these blood markers correlate with how well your immunotherapy is working, with results measured for up to 24 months. The study is currently unclear on its recruitment status and plans to enroll 30 participants.

Study design
This is a prospective pilot study, meaning it will follow participants forward in time. It plans to enroll 30 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The study will measure results for up to 24 months to see how plasma cfRNA PD-L1 expression correlates with treatment and response.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06849518

Study of Longitudinal Plasma PD-L1 Testing With Immunotherapy in Lung Cancer

Recruiting
NAAll AgesInterventionalDiagnostic
Ballad Health
~30 participants
Updated 2025-02-28 on ClinicalTrials.gov
What's tested:Circulogene liquid biopsy testing

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Correlation of plasma cfRNA PD-L1 by qPCR expression* with ICI treatment and response.
Measured over up to 24 months
Lung Cancer (NSCLC)
1 sites across 1 states
Tennessee1

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  • Correlation of plasma cfRNA PD-L1 by qPCR expression* with ICI treatment and response.up to 24 months

    Circulogene ImmunoClear Assay