Glaucoma Screening for At-Risk Californians

This study is looking at ways to find glaucoma early in people who might be at higher risk. Glaucoma is an eye disease that can cause vision loss if not treated. The study will compare two approaches: one group will receive an educational brochure about glaucoma screening, and another group will be offered a glaucoma screening using special eye tests like optical coherence tomography (OCT), color fundus photography, and tonometry (which measures eye pressure). Researchers want to see if the screening tests lead to more people being diagnosed with glaucoma or being identified as needing treatment within three months. You may be able to join if you are Black and 50 or older, Hispanic and 65 or older, or have diabetes and are 50 or older, and have recently visited a Federally Qualified Health Center.

Study design
This is an interventional study planning to enroll 2000 participants. It is a randomized trial comparing glaucoma screening with education alone or delayed intervention.
What's involved
Participants will either receive an educational brochure by mail or be offered a screening appointment. The screening appointment includes visual acuity, OCT, color fundus photography, tonometry, and visual field testing.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome of glaucoma diagnosis or suspect requiring treatment will be measured at 3 months from randomization. Other benefits will be assessed one year after screening.

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NCT06854198

Glaucoma Screening to Enhance At-Risk Californians' Health

Recruiting
NAAges 50+InterventionalScreening
University of California, San Francisco
~2,000 participants
Updated 2026-04-15 on ClinicalTrials.gov
What's tested:Glaucoma screening with optical coherence tomography (OCT), color fundus photography, and tonometryEducational Brochure

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Glaucoma Diagnosis or Glaucoma Suspect Requiring Treatment
Measured over 3 months from randomization
Glaucoma
2 sites across 1 states
California2
  • Jeremy D Keenan, MD, MPH · PRINCIPAL_INVESTIGATOR · University of California, San Francisco
  • Yvonne Ou, MD · PRINCIPAL_INVESTIGATOR · University of California, San Francisco

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Eligibility criteria

Inclusion

Black people aged 50 years or older
Hispanic people aged 65 years or older
People with diabetes aged 50 years or older
Must have been seen at the Federally Qualified Health Center (FQHC) within the past month

Exclusion

Patients without a valid phone number or mailing address
Patients who have had an optometry appointment within the past year
  • Glaucoma Diagnosis or Glaucoma Suspect Requiring Treatment3 months from randomization