Prism Conformity Trial for PTSD in Adolescents

This study is testing a device called Prism for adolescents aged 12 to 21 who have Post-Traumatic Stress Disorder (PTSD). Prism is a software that uses brainwave signals (EEG) to help train patients to reduce their PTSD symptoms. The main goal of this study is to see if Prism is safe for adolescents and to confirm that it helps reduce PTSD symptoms, similar to what has been seen in adults. You could join if you are 12-21 years old, have a PTSD diagnosis for at least a year, and for those under 18, your legal guardian can give consent. The study is currently unclear on its recruitment status.

Study design
This is a single-arm, open-label study, meaning all participants will receive the Prism treatment, and everyone will know what treatment is being given. Up to 45 participants will be enrolled.
What's involved
Participants will complete 15 (plus or minus 3) neurofeedback training sessions with Prism, delivered twice a week over about 8 weeks. There will be assessments during and at the end of the training.
Compensation
Not stated in the trial record.
Follow-up
Participants will have a follow-up assessment one month after their last Prism training session.

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NCT06854328

The Prism Conformity Trial for Post-Traumatic Stress Disorder in Adolescents

Recruiting
NAAges 12–21InterventionalTreatment
GrayMatters Health Ltd.
~45 participants
Updated 2026-05-05 on ClinicalTrials.gov
What's tested:Prism

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Safety reporting
Measured over 1 month
Post-Traumatic Stress Disorder in Adolescence
2 sites across 2 states
New York1
Israel1
  • ADAR SHANI · STUDY_DIRECTOR · GrayMatters Health

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  • Safety reporting1 month

    The primary objective of the study is to extend the use of the FDA cleared Prism for PTSD (K222101) to an adolescent population and to confirm the safety of Prism, by closely following and analyzing device-related serious adverse events. The success criterion is defined by no serious adverse event which is deemed as device-related during the study and one month after treatment ends.