NCT06854991

Healthy Children and Virtual Reality Mediation of Simulated Pain

Enrolling by Invitation
NAAges 6–17Interventional
Nationwide Children's Hospital
~20 participants
Updated 2026-03-17 on ClinicalTrials.gov
What's tested:Active VR-PATPassive VR-PATiPad

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Difference in brain activation picked up on fNIRS between the active VR, passive VR, iPad game, and control conditions
Measured over Assessed continuously throughout the simulated pain session (60 minutes) for one visit
Acute Pain
Experimental Pain in Healthy Human Participants
Children
Adolescents
1 sites across 1 states
Ohio1
  • Henry Xiang, MD, MPH, PhD, MBA · PRINCIPAL_INVESTIGATOR · Nationwide Children's Hospital

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Age 6-17 years, inclusive
Subjects and legal guardians can communicate (read and write) using English

Exclusion

Currently experiencing any pain (acute or chronic)
Took any pain medication within the past 12 hours
Vision, hearing, or cognitive/motor impairments preventing valid administration of study measures
History of motion sickness, seizure disorder, dizziness, or migraine headaches precipitated by visual auras
Minors in foster care, incarcerated, or currently pregnant
  • Difference in brain activation picked up on fNIRS between the active VR, passive VR, iPad game, and control conditionsAssessed continuously throughout the simulated pain session (60 minutes) for one visit

    Mean within subject fNIRS signals of brain activation