Radiosurgery for Brain Metastases
This study is looking at how different treatment margins affect radiosurgery for brain metastases (cancer that has spread to the brain). Radiosurgery uses a focused, high dose of radiation to treat tumors. The study will compare using a 0mm margin versus a 2mm margin around the tumor during treatment. You may be able to join if you are 19 or older, have brain metastases that are 4 cm or less, and don't need retreatment for the same tumor. Researchers will measure the difference in tumor control and side effects at 12 months to see which margin is better. The study plans to enroll 180 participants, but its current status is unclear.
- Study design
- This is an interventional study comparing two different radiosurgery margins for brain metastases, with 180 planned participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Researchers will follow up to measure the difference in outcomes at 12 months.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Trial of Differential Margins in Single Isocenter Radiosurgery of Brain Metastases
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- John A Fiveash, MD · PRINCIPAL_INVESTIGATOR · The University of Alabama at Birmingham
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Difference between 0mm and 2mm12 months
Fisher's Exact Test to determine if (per patient) uncomplicated control is improved or worsened with the addition of a 2mm PTV margin in the treatment of brain metastases with single isocenter radiosurgery.