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TUNE In 3.0 for Adults with Autism Spectrum Disorder

This study is testing a new program called TUNE In (Training to Understand and Navigate Emotions and Interactions) for adults with autism spectrum disorder (ASD). TUNE In is a behavioral treatment designed to help improve social skills, reduce social anxiety, and boost social motivation. Researchers want to see if TUNE In can improve how adults with ASD interact socially. You might be able to join if you are an adult (18 or older) with an ASD diagnosis and a specific score on a social responsiveness survey. The study plans to enroll 40 people, but its current status is unclear.

Study design
This is a randomized study, meaning participants will be assigned by chance to different groups. It aims to enroll 40 adults.
What's involved
Participants will need to complete screening surveys (outcome measures). The study will track your social responsiveness from enrollment up to 6 months.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 6 months after enrollment to measure social responsiveness.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06859918

Randomized Clinical Trial of TUNE In 3.0: A Social/Emotional Program for Adults With Autism Spectrum Disorder

Recruiting
NAAges 18+InterventionalTreatment
University of Pennsylvania
~40 participants
Updated 2026-03-13 on ClinicalTrials.gov
What's tested:TUNE In: Training to Understand and Navigate Emotions and Interactions

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Social Responsiveness Scale (SRS) - Self Report
Measured over From enrollment to 6 months follow up

Conditions

Autism Spectrum Disorder
Autism
Autistic Disorder
Asperger Syndrome

Explore related trials

Autism Spectrum Disorder

NCT06859918

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Brodkin Lab: Perelman School of Medicine, Department of Psychiatry, University of Pennsylvania

    Philadelphia, Pennsylvaniastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Edward Brodkin, MD · PRINCIPAL_INVESTIGATOR · University of Pennsylvania

Who to contact

Edward Brodkin, M.D
[email protected]
215-746-4100
Email the study team

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Eligibility criteria

Inclusion

18 years of age or older
Meet ASD diagnostic criteria supported by an outside diagnostic evaluation and/or by the clinical and developmental information gathered from a phone screen
Be willing to complete screening surveys (outcome measures)
Social Responsiveness Score, Second Edition, self-report SRS survey score of greater than or equal to 60

Exclusion

Severe self-injurious or aggressive behaviors; or with suicidal or homicidal ideation or behaviors (e.g. suicide attempt) within the last 6 months
Major mood episode (major depressive episode, manic episode), psychotic symptoms, or a psychiatric hospitalization within the last 6 months
A history of intellectual disability or low Shipley-2 score

What this trial measures

  • Social Responsiveness Scale (SRS) - Self ReportFrom enrollment to 6 months follow up

    A 65 item self-report measure that identifies the presence and severity of social impairment within the autism spectrum.