This study is for adults aged 18-99 who have had a cochlear implant for over a year and experienced severe hearing loss after age 16. It aims to understand how the brain processes speech in noisy environments for people with cochlear implants. Researchers will use PET neuroimaging (a type of brain scan) with a special radioactive water, O-15, to see which brain areas are active during speech understanding. The goal is to identify what helps cochlear implant users hear better in noisy situations. This study is currently unclear regarding its recruitment status and plans to enroll about 120 cochlear implant users.

Study design

This interventional study plans to enroll about 120 cochlear implant users and an age-matched control group. It will examine brain activity during auditory stimulation.

What's involved

You would undergo PET neuroimaging during auditory stimulation in a single session. This involves an injection of O-15 and a PET/CT scan.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint, identifying cortical bases for speech-in-noise understanding, is measured at the Baseline Visit. No further follow-up is specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.