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NCT06860464

Remote Ischemic Conditioning and Spinal Reflex Modulation

Enrolling by Invitation
NAAges 18–40InterventionalTreatment
East Carolina University
~30 participants
Updated 2026-01-16 on ClinicalTrials.gov
What's tested:Remote Ischemic Condtioning (RIC)Sham ConditioningBalance training

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in maximal H-reflex amplitude (Hmax)
Measured over Baseline, Day 7
+1 more outcome measured

Conditions

Healthy Young Adults

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Healthy Young Adults

Where it's being run

1 sites across 1 states
North Carolina1

Study leadership

  • Swati M Surkar, PT, PhD · PRINCIPAL_INVESTIGATOR · East Carolina University

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Healthy adults 18-40 years of age

Exclusion

Individuals with cognitive deficits or communication problems
Individuals with impaired vision
Individuals with balance disorders such as vestibular disorders, etc.
Individuals who are pregnant
Individuals with known cardiorespiratory dysfunctions
Presence of lower extremity condition, injury, or surgery within last three months which could compromise training

What this trial measures

  • Change in maximal H-reflex amplitude (Hmax)Baseline, Day 7

    The maximal (peak) H-reflex amplitude will be determined from the recruitment (stimulus-response) curve. The Hmax amplitude provides an estimate of the number or proportion of motor neurons (MNs) activated from the total MN pool, reflecting spinal reflex modulations and spinal neuroplasticity.

  • Change in Hmax/ Mmax RatioBaseline, Day 7

    The maximal H-reflex and maximal M-wave amplitudes will be determined from the recruitment curve procedure. Calculating the Hmax/Mmax ratio is a standardization method used to reduce variability in H-reflex amplitude across participants. This provides a better basis for comparison and a more reliable estimate of changes in spinal reflex modulations between participants.