Project UPLIFT for Epilepsy
This study is testing a program called Project UPLIFT for people with epilepsy. Project UPLIFT is a Mindfulness-based Cognitive Behavioral Therapy program that teaches skills like challenging thoughts, coping, problem-solving, and mindfulness to improve well-being. The program involves weekly group sessions delivered remotely over 8 weeks. To join, you must be an adult aged 18 or older with a self-reported diagnosis of epilepsy, speak English, and have access to a phone or computer. The study will measure success by looking at changes in your mood (using the Patient Health Questionnaire), quality of life related to epilepsy, and overall quality of life. The current recruitment status is unclear.
- Study design
- This interventional study plans to enroll 60 participants. It is not specified if it is randomized or blinded.
- What's involved
- You would participate in weekly sessions over 8 weeks. Your mood and quality of life would be measured at the start, at 3 months, and at 6 months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your progress will be followed for 6 months after starting the program.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Implementation and Cost Evaluation of Project UPLIFT
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Cam Escoffery, PhD, MPH · PRINCIPAL_INVESTIGATOR · Emory University
- Katie Bullinger, MD, PhD · PRINCIPAL_INVESTIGATOR · Emory University
- Robin McGee, PhD, MPH · PRINCIPAL_INVESTIGATOR · Emory University
- David H Howard, PhD · PRINCIPAL_INVESTIGATOR · Emory University
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Patient Health Questionnaire (PHQ-8) ScoreBaseline, Month 3, Month 6
The effectiveness of Project UPLIFT is assessed by examining depressive symptoms. The Patient Health Questionnaire (PHQ-8) is an 8-item instrument asking how often respondents have been bothered by certain problems over the past two weeks. Responses are given on a 4-point scale where "not at all" = 0 and "nearly every day" = 3. Total scores range from 0 to 24 where higher scores indicate increased symptoms of depression.
- Quality of Life in Epilepsy (QOLIE-10) ScoreBaseline, Month 3, Month 6
The effectiveness of Project UPLIFT is assessed by examining quality of life. The Quality of Life in Epilepsy (QOLIE-10) instrument has 10 questions about health and daily activities. Responses are given on a range of scales, from 1 (the most positive quality of life) to 4 or 6 (the most negative quality of life). Some items are reverse scored. The final score is the average of scores for the individual items. Lower scores indicate greater quality of life while higher scores indicate greater problems from epilepsy.
- Quality of Patient-Reported Outcomes Measurement Information System (PROMIS): PROMIS-Preference (PROPr) ScoreBaseline, Month 3, Month 6
The effectiveness of Project UPLIFT is assessed by examining health utility. The PROMIS-Preference (PROPr) focuses on 7 PROMIS domains of: Cognitive Function - Abilities; Depression; Fatigue; Pain Interference; Physical Function; Sleep Disturbance; and Ability to Participate in Social Roles and Activities. The PROPr scoring system has single-attribute scoring functions and a multiplicative multi-attribute scoring function for the 7 PROMIS domains. For the single-attribute scoring functions, 0 = the unhealthiest level of the domain and the healthiest levels on all other domains (disutility of the domain under examination), while 1 = utility of full health. For the multi-attribute scoring function, 0 = the utility of dead, and 1 = the utility of full health.