Back to search results

Well-being in IBS: Strengths and Happiness (WISH) 2.0 Study

This study, called WISH 2.0, is looking at two different approaches for people with Irritable Bowel Syndrome (IBS). One approach is a Positive Psychology (PP) Intervention, which involves 9 weekly phone sessions where you'll learn and practice exercises to improve your well-being. The other is an Educational Intervention, which also involves 9 weekly phone sessions with educational exercises. The study wants to see if these interventions are practical, acceptable, and how they might affect IBS symptoms. You can join if you are an adult with an IBS diagnosis (meeting Rome IV criteria), speak English, and have access to a phone. The study will measure how many sessions you complete and how easy and useful the weekly exercises are. The current status of the study is unclear.

Study design
This is an interventional study with a planned enrollment of 50 participants. It compares a Positive Psychology (PP) Intervention to an Educational Intervention.
What's involved
You would complete 9 weekly 30-minute phone sessions with a study interventionist and independently complete exercises between sessions.
Compensation
Not stated in the trial record.
Follow-up
The study measures outcomes weekly during the intervention (weeks 1-8) and post-intervention (week 9).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06866106

Well-being in IBS: Strengths and Happiness (WISH) 2.0

Recruiting
NAAges 18+InterventionalTreatment
Massachusetts General Hospital
~50 participants
Updated 2026-06-22 on ClinicalTrials.gov
What's tested:Positive Psychology (PP) InterventionEducational Intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Proportion of Intervention Sessions Completed by Participants
Measured over Post-intervention at 9 weeks
+2 more outcomes measured

Conditions

Irritable Bowel Syndrome

Explore related trials

Irritable Bowel Syndrome

Where it's being run

1 sites across 1 states
Massachusetts1

Study leadership

  • Elizabeth N Madva, MD · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital

Who to contact

Elizabeth N Madva, MD
[email protected]
617-724-6300 · ext. 111-134-2334
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

IBS Diagnosis: Adult patients with an IBS diagnosis meeting standardized Rome IV diagnostic criteria.
Language and communication: English fluency and access to a phone.

Exclusion

Presence of inflammatory bowel disease or other structural/biochemical primary gastrointestinal illness that better explains IBS-like symptoms: As reported by the patient, their physician, and/or documented in the medical record.
Severe psychiatric illness: Current manic episode, psychosis, or active substance use disorder diagnosed via the Mini International Neuropsychiatric Interview (MINI) or Diagnostic Interview for Anxiety, Mood, and OCD and Related Neuropsychiatric Disorders (DIAMOND).
Cognitive impairment: Assessed using a six-item cognitive screen developed for research.
Presence of atrial fibrillation or a cardiac pacemaker, or daily use of beta blocking medication: As reported by the patient and/or documented in the medical record.
Plans to start or participate in another new behavioral health intervention or psychotherapy during the study period.

What this trial measures

  • Proportion of Intervention Sessions Completed by ParticipantsPost-intervention at 9 weeks

    Feasibility will be measured by the proportion of intervention sessions completed by participants. The intervention will be considered feasible if at least 50% of participants complete at least 6/9 sessions.

  • Ease of Weekly ExercisesWeekly during intervention (weeks 1-8) and post-intervention (week 9)

    Participants will provide ratings of ease after each weekly exercise, measured on a 10-point Likert scale (0=very difficult, 10=very easy).

  • Utility of Weekly ExercisesWeekly during intervention (weeks 1-8) and post-intervention (week 9)

    Participants will provide ratings of utility after each weekly exercise, measured on a 10-point Likert scale (0=not at all helpful; 10=very helpful).