QRX-3 for Chronic Kidney Disease Progression

This study is looking at a new drug called QRX-3 to see if it can help prevent and treat the worsening of chronic kidney disease (CKD), acute kidney injury, and kidney failure. QRX-3 is a capsule designed to improve how your kidney cells work by helping with a process called NAD/NAD+ redox pathway. We are looking for 3000 adults, aged 18 to 90, who have chronic kidney disease with a specific level of kidney function (eGFR less than 60mls/min) and a slow decline in their kidney function over the past year. The main goal is to see if QRX-3 can improve your kidney function, measured by your Glomerular filtration rate (eGFR), after one year. The current recruitment status is unclear.

Study design
This is an interventional study, meaning participants will receive a specific treatment. The phase of the study is not specified, and it plans to enroll 3000 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured at 1 year, suggesting participants will be followed for at least this duration.

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NCT06866236

Use of New Drug QRX-3 for Prevention and Treatment of Chronic Kidney Disease Progression

Not Yet Recruiting
PHASE2Ages 18–90InterventionalTreatment
Ebima Clifford Okundaye
~3,000 participants
Updated 2025-09-08 on ClinicalTrials.gov
What's tested:QRX-3

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
change in Glomerular filtration rate
Measured over 1 year
Chronic Kidney Diseases
Acute Kidney Injury
Kidney Failure
1 sites across 1 states
Texas1

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Eligibility criteria

Inclusion

Patient with Chronic kidney disease
Estimated Glomerular function by MDRD of less than 60mls/min
Patients with declining renal function ( as measured by eGFR by MDRD )
Rate of decline of eGFR over the last one year of less than 20%
Negative Serology markers for CKD etiology
Provider perceived adherence to study follow up

Exclusion

Symptomatic renal failure
Presence of any suspected Acute renal failure superimposed
Presence of cast , hematuria, or abnormal urinalysis outside of simple UTI
No known reversible cause of renal decline
  • change in Glomerular filtration rate1 year

    change percentage in kidney function level measured with cystatin creatinine glomerular filtration rate