Validating a Myasthenia Gravis Screening Program

This study is looking for adults across the United States who have undiagnosed muscle weakness or fatigue. It's a remote study, meaning you can participate from home. The main goal is to see how well a self-assessment tool works at identifying people who might have myasthenia gravis (MG), a condition that causes muscle weakness. You'll be recruited through social media and asked to complete online surveys and simple physical tests at home. If the tests suggest you might have MG, you'll be encouraged to see a doctor for further evaluation. This study builds on a previous one that successfully helped diagnose MG in some participants. The study aims to enroll 1000 people, but its current recruitment status is unclear.

Study design
This is a remote, observational study aiming to enroll 1000 participants. It is not a drug trial but rather validates a screening program.
What's involved
You will complete online surveys and self-administered physical tests. If recommended, you will follow up with a clinician.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, self-assessment tool validity, is measured at 6 months from enrollment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06866483

Validation and Scaling of Screening Program for Undiagnosed Myasthenia Gravis-Social Media Campaign Paired With a Self-moderated Assessment

Recruiting
Not specifiedAges 18+Observational
ZS Associates
~1,000 participants
Updated 2025-03-10 on ClinicalTrials.gov
What's tested:Social media recruitmentSelf-AssessmentFollow-up

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Self-Assessment tool validity
Measured over 6 months from time of enrollment
Myasthenia Gravis
Neuromuscular Disease
Neuromuscular Manifestations
1 sites across 1 states
Illinois1

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Reside within the 50 states of the United States at the time of enrollment
Age 19 or older if reside in Nebraska or Alabama, Age 21 or older if reside in Mississippi, Age 18 years or older if reside in any other state
Active email account
Fluency in English (spoken / written), as demonstrated by the ability to read and sign the Informed Consent Form

Exclusion

Live in an overseas territory of the United States
Inability or unwillingness to provide written informed consent
Diagnosed myasthenia gravis, including sero-negative MG\*
Diagnosed multiple sclerosis
Have speech impairment, eye/arm/leg weakness due to diagnosed brain cancer, or stroke
  • Self-Assessment tool validity6 months from time of enrollment

    Measure the specificity and sensitivity of the Self-Assessment tool