PROTECT Registry for Thyroid Embolization

This study is a registry, meaning it collects information from patients who have already received a treatment called Pressure-enabled Retrograde Occlusive Therapy With Embolization (PED-TAE) using the TriNav Infusion System for thyroid conditions like hyperthyroidism or goiter. The goal is to understand how this treatment affects your quality of life and to gather information on its safety and effectiveness, such as how much the thyroid shrinks and changes in thyroid function. You might be able to join if you are between 18 and 89 years old and have already had PED-TAE with the TriNav system for hyperthyroidism or a large toxic nodule. The study will look at your quality of life using a questionnaire and track any side effects for 6 months after your procedure. The current recruitment status is unclear.

Study design
This is an observational study, meaning researchers will collect data from your medical records after you've had your treatment. It aims to include 100 participants.
What's involved
After your PED-TAE treatment, information from your patient charts will be collected in a study database. You will also complete a quality of life questionnaire.
Compensation
Not stated in the trial record.
Follow-up
Your quality of life and any procedure-related side effects will be tracked for 6 months after your treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06868459

Pressure-enabled Retrograde Occlusive Therapy With Embolization for Control of Thyroid Disease (PROTECT Registry): A Multicenter Registry

Enrolling by Invitation
Not specifiedAges 18–89Observational
Sarasota Memorial Health Care System
~100 participants
Updated 2025-09-08 on ClinicalTrials.gov
What's tested:Data Collection

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
ThyPro-39 questionnaire
Measured over 6 months
+1 more outcome measured
Hyperthyroidism; Goiter
Multinodular Goiter
Thyroid Nodules
Thyroid Disease
Hyperthyroidism
Toxic Multinodular Goiter

NCT06868459

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Sarasota Memorial Health Care System

    Sarasota, Floridano site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Tamela Fonseca, PhD, RN, CCRC, NE-BC · STUDY_DIRECTOR · Sarasota Memorial Health Care System

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • ThyPro-39 questionnaire6 months

    Change in quality of life as measured by ThyPro-39 questionnaire at 6-months (+/- 60). Responses to each statement are measured on a Likert scale ranging from '0= no symptoms or problems' to '4= severe symptoms or problems' based on the period of the last 4 weeks. Higher scores indicate greater impact on quality of life due to thyroid issues.

  • Procedure related adverse events6 months

    Safety as measured by the rate of procedure related adverse events as measured by SIR criteria at 2-weeks (+/- 7 days), 3- (+/- 30 days) and 6-months (+/- 60 days) post PED-TAE using TriNav treatment.