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Study Comparing Genicular Artery Embolization to Steroid Injections for Knee Osteoarthritis

This study is comparing two treatments for knee osteoarthritis (OA) pain: genicular artery embolization (GAE) and corticosteroid injection. GAE is a procedure that blocks small arteries around the knee. Corticosteroid injection involves injecting a steroid medication directly into the knee joint. Researchers want to see which treatment is better at reducing knee pain and improving function, measured by the WOMAC score (a questionnaire about pain, stiffness, and physical function) at 6 and 12 months. They will also track any serious side effects for up to 12 months. You may be able to join if you have localized knee pain and are a suitable candidate for an arterial vascular access procedure. The study is currently recruiting 126 participants aged 40 and older, of all genders.

Study design
This is a multi-center, prospective, randomized study involving 126 participants. Participants will be randomly assigned to receive either genicular artery embolization or corticosteroid injection.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to 12 months after treatment to assess pain, function, and serious adverse events.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06872567

Randomized Controlled Study Evaluating Genicular Artery Embolization Against Intra-Articular Corticosteroid Knee Injection for Osteoarthritic Knee Pain

Recruiting
NAAges 40+InterventionalTreatment
North American Science Associates Ltd.
~126 participants
Updated 2025-11-24 on ClinicalTrials.gov
What's tested:genicular artery embolizationCorticosteroid Injection

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
Measured over 6 and 12-month post treatment
+1 more outcome measured

Conditions

Knee Osteoarthritis (Knee OA)

Explore related trials

Osteoarthritis of knee

NCT06872567

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Virginia

    Charlottesville, Virginiano site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

Ziv J Haskal, MD
[email protected]
16463691570
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

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Eligibility criteria

Inclusion

Patient has localized knee pain
Must be an appropriate candidate for arterial vascular access procedure

Exclusion

Known sensitivity or allergy to implant materials
Unable or unwilling to comply with study requirements

What this trial measures

  • Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)6 and 12-month post treatment

    Changes in total Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score. Scale ranges from 0 to 96 with higher scores equating to greater pain, stiffness and difficulty with activities of daily living.

  • Serious Adverse Events (SAE)Treatment, 1,3,6,9 and 12-month post treatment