NCT06873204

Impact of Soluble Arabinoxylan and Rice Bran Fiber on the Gut Microbiome in Healthy Adults

Not Yet Recruiting
NAAges 18–45InterventionalBasic science
Purdue University
~25 participants
Updated 2025-06-29 on ClinicalTrials.gov
What's tested:Soluble ArabinoxylanRice BranMaltodextrin (Placebo)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Comparison of two test fibers (insoluble cereal bran and soluble arabinoxylan) and a control (maltodextrin) on gut beneficial bacteria
Measured over From enrollment to the end of treatment at 13 weeks.
Healthy
1 sites across 1 states
Indiana1

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Eligibility criteria

Inclusion

Men or women.
Aged between 18-45 years.
Body mass index between 18.5 and 25 kg/m².
Able to read/speak English.

Exclusion

Gastrointestinal disorders (inflammatory bowel disease, irritable bowel syndrome, gluten sensitivity/intolerance, etc.).
Those who took antibiotics 3 months before the study.
Individuals taking regular medication or supplements that might affect the gut microbiota.
Individuals undertaking weight-loss diets.
Unstable body weight (±3 kg in the past 3 months), and individuals below 110 lb.
Heavy drinkers (for men, consuming more than 4 drinks on any day or more than 14 drinks per week; for women, consuming more than 3 drinks on any day or more than 7 drinks per week).
Smokers (those who have smoked 100 cigarettes in their lifetime and who currently smoke cigarettes, even every day or occasionally).
Breastfeeding or pregnant women.
  • Comparison of two test fibers (insoluble cereal bran and soluble arabinoxylan) and a control (maltodextrin) on gut beneficial bacteriaFrom enrollment to the end of treatment at 13 weeks.

    The primary outcome of the study is change in butyrogenic Clostridium cluster XIVa gut bacteria.