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Weight Management for Endometrial Cancer Survivors

This study is looking at how doctors can help early-stage endometrial cancer survivors who are overweight or obese manage their weight. You might be eligible if you are a woman aged 18 or older, have a BMI of 30 or higher, and have completed surgery for stage 1 endometrioid endometrial adenocarcinoma. The study aims to see how many participants referred to a weight loss clinic start weight management medications like GLP-1 agonists, naltrexone/bupropion, orlistat, or phentermine/topiramate within 12 months. This research is important because obesity can affect the long-term health of endometrial cancer survivors more than their cancer diagnosis.

Study design
This is an observational study involving 50 participants. It looks at how patients engage with weight management programs.
What's involved
You will be referred to a weight management clinic to discuss options. If you choose medication, data from your routine monitoring will be collected.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome is measured at 12 months after referral to the weight loss clinic.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06877572

Weight Loss Management in Endometrial Cancer Survivors

Active, Not Recruiting
Not specifiedAges 18+Observational
University of Kansas Medical Center
~50 participants
Updated 2026-08-12 on ClinicalTrials.gov
What's tested:Weight loss with pharmacotherapyWeight loss without pharmacotherapy

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percentage of participants referred to weight loss clinic who are able to start weight management medications
Measured over 12 months

Conditions

Endometrial Cancer Survivors
Weight Management
Early Stage Endometrial Cancer

Explore related trials

Endometrial Carcinoma

Where it's being run

1 sites across 1 states
Kansas1

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

≥18 years old
ECOG 0-2
BMI ≥ 30kg/m2
Completed surgical staging with no evidence of residual disease
Endometrioid endometrial adenocarcinoma, p53 wild type
Stage 1
Undergoing active surveillance +/- brachytherapy

Exclusion

Unable to participate in behavior weight loss
Stroke, heart attack, end stage liver disease, or end stage kidney disease during the last 6 months.
Currently on a GLP-1 agonist
Currently on insulin

What this trial measures

  • Percentage of participants referred to weight loss clinic who are able to start weight management medications12 months

    We will track the number of participants who do and do not start medication. Patients will be offered GLP-1 agonist, naltrexone/bupropion, orlistat, or phentermine/topiramate based discussion with weight management specialist.