Digital Intervention for Depression and Cannabis Use
This study is testing a smartphone app called Amplification of Positivity - Cannabis Use (AMP-C) for people experiencing both depression and problematic cannabis use. AMP-C aims to improve your mood by focusing on positive events. Researchers want to see if this app helps reduce symptoms of depression (Major Depressive Disorder) and cannabis use. You might be able to join if you are at least 18 years old, live in the United States, and have moderate depression and problematic cannabis use. The study will compare the AMP-C app to symptom tracking. The main goals are to see how much your depression symptoms and cannabis use change, and how easy the app is to use. The study plans to enroll 80 people, but its current status is unclear.
- Study design
- This interventional study plans to enroll 80 participants. You will be randomly assigned to either use the AMP-C app or track your symptoms.
- What's involved
- You will complete the intervention and then have follow-up assessments at several time points, including immediately after the intervention, at 4 weeks, and at 1, 3, 6, and 12 months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your depressive symptoms and cannabis use will be tracked for up to 12 months after you complete the intervention.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in Depressive Symptoms (Patient Health Questionnaire-9; PHQ-9)Baseline, Primary Endpoint: Post-Intervention (approximately one week after completing intervention), Secondary Endpoints: Intervention Midpoint (4 weeks into intervention), 1-, 3-, 6-, and 12-months after completing intervention
Depressive symptoms will be measured with the Patient Health Questionnaire-9 (PHQ-9). The PHQ-9 is a widely-used 9-item self-report measure that assesses depressive symptom severity over the previous two weeks. Scores on the PHQ-9 range from 0-27, with greater scores indicating greater depression severity.
- Change in Cannabis Use Frequency (Daily Sessions, Frequency, Age of Onset, and Quantity of Cannabis Use Inventory; DFAQ-CU)Baseline, Primary Endpoint: Post-Intervention (approximately one week after completing intervention), Secondary Endpoints: Intervention Midpoint (4 weeks into intervention), 1-, 3-, 6-, and 12-months after completing intervention
Cannabis use use will be measured with the Daily Sessions, Frequency, Age of Onset, and Quantity of Cannabis Use Inventory (DFAQ-CU). The DFAQ-CU is a 24-item self-report measure that assesses frequency, age of onset, and quantity of cannabis use. There are six factors: daily sessions, frequency, age of onset, marijuana quantity, concentrate quantity, and edible quantity. The six factors, except age of onset, are independently scored, and higher scores indicate greater cannabis use. Our primary outcome will assess changes in frequency.
- Usability (System Usability Scale; SUS)Post-Intervention (approximately one week after completing intervention)
The System Usability Scale (SUS) is a 10-item self-report measure commonly used to assess the degree to which participants endorse ease of use following task-based operation of computer systems (i.e., perceived usability). Total scores on the SUS range from 0 to 100, with greater scores indicating greater usability. An average score of 68 or greater on the SUS in our AMP-C group will indicate acceptable usability.