Dose Response of Exercise for Arthritis Management

This study is looking at how different amounts of physical activity can help manage symptoms for people with arthritis, rheumatoid arthritis (RA), gout, fibromyalgia (FM), or osteoarthritis. You would be assigned to one of three physical activity goals (45, 90, or 150 minutes per week) and receive a 6-month program called DREAM Adaptive Intervention. This program includes monthly phone coaching, a Walk With Ease Guidebook, behavioral lessons, and a Fitbit to help you reach your goals. The study will measure your physical function using a 6 Minute Walk Test to see if the exercise program helps. This study is currently recruiting and aims to enroll 285 participants who are 18 or older, have a doctor-diagnosed form of arthritis, and can read and write in English.

Study design
This is an interventional study where participants are randomly assigned to one of three physical activity goals. It plans to enroll 285 participants.
What's involved
You would participate in a 6-month physical activity program, including monthly phone coaching and using a Fitbit. Your physical function will be measured at the beginning and after 6 months.
Compensation
Not stated in the trial record.
Follow-up
Your physical function will be measured at the start of the study and again at 6 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06880653

Dose Response of Exercise for Arthritis Management

Recruiting
NAAges 18+InterventionalTreatment
University of South Carolina
~285 participants
Updated 2026-04-03 on ClinicalTrials.gov
What's tested:DREAM Adaptive Intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Physical function (6 Minute Walk Test)
Measured over Baseline to 6 months
Arthritis
Rheumatoid Arthritis (RA)
Gout
Fibromyalgia (FM)
Osteoarthritis
Lupus Erythematosus, Systemic
1 sites across 1 states
South Carolina1
  • Christine Pellegrini, PhD · PRINCIPAL_INVESTIGATOR · University of South Carolina

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Eligibility criteria

Inclusion

18 years or older
Have a doctor diagnosed form of arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia
Ability to read and write in English

Exclusion

Have any contraindications to exercise (besides arthritis)
Engage in \>45 min/week of Actigraph assessed moderate to vigorous intensity activity
Are pregnant, breastfeeding, or planning to become pregnant in the next year
Are planning to relocate out of the Columbia, SC area in the next 12 months,
Do not have a device compatible with Fitbit
Have uncontrolled hypertension (e.g., systolic blood pressure \> 160 mmHg or diastolic blood pressure \> 100 mmHg)
Plan to have a surgery that affects mobility in the next 12 months
Have a serious cognitive impairment.
Not willing to be randomized to any of the 3 conditions, do not believe they could adhere to the goals, or do not believe they could achieve the highest dose of activity (150 minutes/week).
  • Physical function (6 Minute Walk Test)Baseline to 6 months

    Change in distance walked during the 6 minute walk test