Diet and Exercise Solutions for Low Blood Pressure After Meals in Spinal Cord Injury

This study is looking at ways to help people with chronic spinal cord injury who experience low blood pressure after eating, a condition called postprandial hypotension. Researchers are testing if a low glycemic load diet (a diet that helps keep blood sugar steady) and lower-body electrical stimulation exercise after meals can reduce this drop in blood pressure. They will compare these interventions to a high glycemic load diet. The study aims to see how much systolic blood pressure (the top number in a blood pressure reading) decreases. You may be able to join if you are between 18 and 65 years old, have a spinal cord injury between C4 and T12, use a wheelchair, and are at least one year post-injury. The current status of the study is unclear, and it plans to enroll 13 participants.

Study design
This is an interventional study, meaning participants will receive specific treatments. It plans to enroll 13 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, magnitude of systolic blood pressure decrease, is measured at Visits 2-4 on Day 1.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06882460

Diet and Exercise Solutions to Postprandial Hypotension

Recruiting
NAAges 18–65InterventionalBasic science
Ohio State University
~13 participants
Updated 2026-04-27 on ClinicalTrials.gov
What's tested:Low glycemic loadElectrical stimulation exerciseHigh glycemic load diet

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Magnitude of systolic blood pressure decrease (in-lab)
Measured over Visit 2-4, Day 1
Spinal Cord Injuries
1 sites across 1 states
Ohio1

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Eligibility criteria

Inclusion

Spinal cord injury (SCI) between C4 and T12 who require use of wheelchair for daily mobility
AIS A or B
\>1-year post-injury

Exclusion

Currently pregnant of breast-feeding
Type 1 or 2 diabetes
Previous gut augmentation bariatric surgery
Neurological impairment other than SCI
History of uncontrolled autonomic dysreflexia
History of bone fractures
Use of abdominal binder or anti-hypotensive drugs
Fitted with pacemaker or defibrillator
Currently receiving electrical stimulation training or in the previous year
  • Magnitude of systolic blood pressure decrease (in-lab)Visit 2-4, Day 1

    Calculated as the maximum decrease in systolic blood pressure in the 2-h after eating breakfast and lunch under laboratory-controlled conditions