Observational Study of Quality of Life After Partial Cystectomy

This study is looking at the health-related quality of life (how well you feel and function) and urinary outcomes (how your bladder works) in people who have had a partial cystectomy (surgery to remove part of the bladder) for bladder cancer. Researchers will compare these outcomes with those of people who had a radical cystectomy (surgery to remove the entire bladder). The goal is to understand how different bladder surgeries affect patients' lives. You might be able to join if you are 18 or older, have had a partial or radical cystectomy, and your medical records can be reviewed. The study aims to enroll 1000 participants. The current recruitment status is unclear.

Study design
This is an observational study involving 1000 planned participants. It compares two groups of patients who have already had surgery for bladder cancer.
What's involved
You would complete questionnaires and have your medical records reviewed. This will happen for up to one year.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to one year to assess health-related quality of life and urinary outcomes.

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NCT06891209

Exploration of HRQOL and Urinary Outcomes Following Partial Cystectomy

Recruiting
Not specifiedAges 18+Observational
Mayo Clinic
~300 participants
Updated 2026-08-11 on ClinicalTrials.gov
What's tested:Non-Interventional Study

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Health-related quality of life - EORTC QLQ-C30
Measured over Up to 1 year
+1 more outcome measured
Bladder Carcinoma

NCT06891209

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Mayo Clinic in Rochester

    Rochester, Minnesotastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Vidit Sharma, MD · PRINCIPAL_INVESTIGATOR · Mayo Clinic

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Eligibility criteria

Inclusion

Currently living partial cystectomy patients in Mayo Urology's cystectomy registry and patients undergoing radical or partial cystectomy
Matched 2:1 living radical cystectomy to partial cystectomy patients
Either urothelial or non-urothelial histology

Exclusion

Partial cystectomy patients that underwent subsequent radical cystectomy
  • Health-related quality of life - EORTC QLQ-C30Up to 1 year

    Assessed using the EORTC Core Quality of Life questionnaire (EORTC QLQ-C30), which is designed to measure cancer patients' physical, psychological and social functions. It is a 30-item questionnaire related to symptoms and activities during the past week. Responses are recorded on a scale of 1-4 where 1=not at all, 2=a little, 3=quite a bit, and 4=very much. Scores among partial cystectomy patients will be compared to radical cystectomy patients.

  • Self-reported urinary outcomesUp to 1 year

    Assessed using the EORTC Quality of Life Questionnaire - Muscle Invasive Bladder Cancer (EORTC QLQ-BLM30), a 30-item questionnaire related to general symptoms experienced during the past week or during the past 4 weeks. Responses are recorded on a scale of 1-4 where 1=not at all, 2=a little, 3=quite a bit, and 4=very much. Scores among partial cystectomy patients will be compared to radical cystectomy patients.