A Study of HS-20110 for Advanced Solid Tumors

This study is testing a drug called HS-20110 in people with advanced solid tumors. HS-20110 is an antibody-drug conjugate, which means it's designed to deliver a drug directly to cancer cells. The main goals are to find the safest dose of HS-20110 and see how well it shrinks tumors. You may be able to join if you are 18 or older and have advanced solid tumors that have been confirmed by a doctor. The study is open-label, meaning both you and your doctors will know you are receiving HS-20110. The study plans to enroll 475 participants.

Study design
This is an open-label study, meaning everyone knows what treatment is being given. It plans to enroll 475 participants with advanced solid tumors.
What's involved
HS-20110 will be given through an IV infusion in 21-day cycles. The study will explore different doses of the drug.
Compensation
Not stated in the trial record.
Follow-up
Your safety will be monitored from the first day of treatment until one month after your last dose. Tumor response will be measured from screening until two months after your last dose.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06892379

A Study of HS-20110 in Participants With Advanced Solid Tumors

Recruiting
PHASE1Ages 18+InterventionalTreatment
Hansoh BioMedical R&D Company
~475 participants
Updated 2026-04-20 on ClinicalTrials.gov
What's tested:HS-20110 (Phase Ia:Dose escalation )HS-20110 (Phase Ib:Dose expansion )

At a glance

Recruiting sites
8 of 8 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Maximum tolerated dose (MTD) or maximum applicable dose (MAD)
Measured over From day 1 to one months after the last dose in Phase 1a
+1 more outcome measured
Solid Tumors

NCT06892379

Where you'd take part

This study runs at 8 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Carolina BioOncology Institute

    Huntersville, North Carolinastudy coordinator listed

    Recruiting

  • BRCR Medical Center INC

    Tamarac, Floridano site contact published

    Recruiting

  • Fort Wayne Medical Oncology and Hematology

    Fort Wayne, Indianano site contact published

    Recruiting

  • NEXT Dallas

    Irving, Texasno site contact published

    Recruiting

  • NEXT Oncology

    San Antonio, Texasno site contact published

    Recruiting

  • NEXT Virginia

    Fairfax, Virginiano site contact published

    Recruiting

  • SUN YAT-SEN University Cancer Center

    Guangzhou, Guangdong, Chinano site contact published

    Recruiting

  • The University of Texas MD Anderson Cancer Center

    Houston, Texasno site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Opens a ready-to-send draft in your own email app — review before sending.

  • Maximum tolerated dose (MTD) or maximum applicable dose (MAD)From day 1 to one months after the last dose in Phase 1a
  • Objective response rate (ORR) as per RECIST v1.1From screening to 2 months after the last dose