Proton SBRT for Spinal Metastasis

This study is looking at a new way to treat spinal metastasis (cancer that has spread to the spine) using a type of radiation called proton SBRT (Stereotactic Body Radiation Therapy). This treatment delivers high doses of radiation very precisely. It's for people whose spinal tumors are difficult to treat with standard radiation. Researchers want to see if they can successfully deliver at least one treatment session to 8 out of 12 participants. You could be eligible if you are an adult with a non-blood cancer that has spread to your spine, and your case is considered complex for standard radiation. The study is currently recruiting a small group of 12 participants.

Study design
This is a single-arm pilot study, meaning all 12 participants will receive the same treatment. It is testing proton SBRT for spinal metastasis.
What's involved
Participants will receive spinal proton SBRT over 5 treatment sessions, which will take approximately 3 weeks to complete.
Compensation
Not stated in the trial record.
Follow-up
The primary goal is measured at the completion of SBRT treatment, which is approximately 3 weeks.

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NCT06895564

Proton SBRT for Spinal Metastasis

Recruiting
NAAges 18+InterventionalTreatment
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
~12 participants
Updated 2026-04-29 on ClinicalTrials.gov
What's tested:Spinal Proton SBRT

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Rate of successful delivery of at least one fraction for 8 of 12 patients with spine metastases
Measured over Completion of SBRT treatment, approximately 3 weeks
Spinal Metastasis

NCT06895564

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Johns Hopkins Hospital

    Baltimore, Marylandstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Kristin Redmond, MD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University

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  • Rate of successful delivery of at least one fraction for 8 of 12 patients with spine metastasesCompletion of SBRT treatment, approximately 3 weeks

    To assess the feasibility of proton SBRT in patients with nonhematologic spine metastases that are unable to be effectively treated with photon SBRT. Feasibility will be determined by a successful delivery of at least one fraction for 8 of 12 patients with spine metastases.