Dairy Choline Bioavailability in Post-menopausal Women

This study is looking at how well your body uses choline from dairy compared to eggs. Researchers want to understand how the body processes choline and what effect Whey Protein Phospholipid Concentrate (WPPC) has on this process. They will compare WPPC to whole egg powder to see if WPPC is just as effective as eggs in providing choline. You would drink a chocolate-flavored drink containing either WPPC or whole egg powder. This study is for women aged 51 to 70 who are post-menopausal (meaning your menstrual periods have stopped permanently for at least 12 months). The main goal is to measure changes in choline levels in your blood over 10 days. The current recruitment status is unclear, and the study plans to enroll 24 participants.

Study design: This is an interventional study planning to enroll 24 post-menopausal women aged 51-70.
What's involved: Participants will drink a chocolate-flavored drink with either WPPC or whole egg powder. Choline levels will be measured from baseline to 10 days.
Compensation: Not stated in the trial record.
Follow-up: Participants will be followed for 10 days after the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

Dairy Choline Bioavailability

Not Yet Recruiting

NAAges 51–70Interventional

University of Wisconsin, Madison

~24 participants

Updated 2026-08-28 on ClinicalTrials.gov

What's tested:WPPCWhole egg powder

At a glance

Recruiting sites

0 of 1 listed site is recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

Change in circulating choline

Measured over Baseline to 10 days

Conditions

Post-menopausal Women

Post-menopausal Status

Where it's being run

1 sites across 1 states

Wisconsin1

Study leadership

Bradley Bolling, PhD · PRINCIPAL_INVESTIGATOR · University of Wisconsin, Madison

Who to contact

Kevin Shih

[email protected]

919-338-9453

Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Ages between 51 and 70

Is currently post-menopausal (Post-menopausal is a term used to describe the time in a woman's life after she has gone through menopause. This usually happens between the ages of 45 and 55. Menopause is when a woman's menstrual periods stop permanently (at least 12 months))

Not allergic to the intervention foods and allergens that are related to the production of intervention foods (e.g. dairy products, egg, fish, peanut, shellfish, soy, tree nuts, wheat, crustaceans, gluten, mollusks, mustard, sesame seeds.)

Had stable body weight (± 5%) for the past 6 months

Free from cancer

Did not have weight loss surgery, colon surgery

Do not have chronic kidney diseases

Do not have malabsorption towards fat and dairy products

Willing to complete health surveys

Willing to complete two 4-day food diaries

Willing to consume the intervention smoothies

Willing to provide blood, urine, fecal samples at baseline and after 10 days of intervention

Exclusion

On weight loss/weight gain diets

Diagnosed with fat malabsorption

Undergoing weight loss surgery

Diagnosed with chronic kidney diseases

Allergic to the intervention foods and allergens that are related to the production of intervention foods (e.g. dairy products, egg, chocolate, fish, peanut, shellfish, soy, tree nuts, wheat, crustaceans, gluten, mollusks, mustard, sesame seeds, banana, strawberry, raspberry, blackberry, blueberry.)

Regularly using antibiotics or probiotics or prebiotics

Regularly using weight-loss drugs (GLP-1, Orlistat, Cetilistat, etc.)

Regularly using laxatives

Unable to avoid strenuous exercise during the study (\>4 h vigorous exercise per day)

What this trial measures

Change in circulating cholineBaseline to 10 days
Circulating choline will be measured by UHPLC-HRMS/MS

Trialytics