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Cryo Nerve Block Registry for Amputation Pain

This study is a registry looking at how a treatment called cryoablation (freezing nerves) is used during amputation surgery. Cryoablation involves using a probe to apply extreme cold to nerves. The goal is to see how this device is used to manage pain after an amputation, including phantom limb pain (pain felt in a missing limb). You might be able to join if you are 18 or older and are having or will have an amputation. The study will look at how participants are doing 30 days after the procedure. The current recruitment status is unclear, and the study plans to enroll 2000 people.

Study design
This is an observational study, meaning researchers will watch how cryoablation is used in 2000 participants. It is not a randomized study where you might receive a placebo.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 30 days after the procedure to assess their outcomes.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06908538

Cryo NerVe Block Extremity AmputatioN RegIStry for Post Operative and pHantom Limb Pain

Recruiting
Not specifiedAges 18+Observational
AtriCure, Inc.
~2,000 participants
Updated 2026-08-26 on ClinicalTrials.gov
What's tested:cryoablation

At a glance

Recruiting sites
6 of 6 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Primary Outcome Measure
Measured over 30 days

Conditions

Amputation
Amputation of Lower Limb
Amputation of Upper Limb
Amputation, Limb Loss
Amputation, Traumatic/Surgery
Cryo Analgesia

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Amputation

NCT06908538

Where you'd take part

This study runs at 6 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Berkshire Medical Center

    Pittsfield, Massachusettsstudy coordinator listed

    Recruiting

  • Elliot Hospital

    Manchester, New Hampshirestudy coordinator listed

    Recruiting

  • Medical College of Wisconsin/Froedtert Hospital

    Milwaukee, Wisconsinstudy coordinator listed

    Recruiting

  • NYU Langone Health

    New York, New Yorkstudy coordinator listed

    Recruiting

  • Ohio State University

    Columbus, Ohiostudy coordinator listed

    Recruiting

  • Prisma Health - Upstate

    Greenville, South Carolinastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

Senior Registry Specialist
[email protected]
1 (866) 349-2342
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

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Eligibility criteria

Inclusion

Patients who have or will have an amputation procedure;
Patients who are willing and capable of providing informed consent;
Patients whose age is 18 years or above, or of legal age to give informed consent specific to state and national law.

Exclusion

Women of childbearing potential who are, or plan to become, pregnant during the time of the study;
Other medical, social, or psychological conditions that in the opinion of the Investigator precludes the subject from appropriate consent or adherence to the protocol.

What this trial measures

  • Primary Outcome Measure30 days

    CryoNerve Block procedural complications