Digital Intervention (ACT on Vaping App) for Vaping Cessation

This study is testing a smartphone app called ACT on Vaping to help young adults quit using e-cigarettes. E-cigarettes can be harmful, and this app aims to provide a modern way to help people stop. You might be able to join if you are 18-30 years old, use e-cigarettes weekly, and have a compatible smartphone. The study will look at whether participants can successfully quit all nicotine and tobacco products, confirmed by a test, six months after starting. The current status of the study is unclear.

Study design
This is an interventional study planning to enroll 1178 participants. Participants will be randomly assigned to one of two groups, both using the ACT on Vaping app.
What's involved
You would use a smartphone app and receive text messages. Your vaping status will be checked via text messages at 2 weeks, 2 months, and 4 months. You will also have follow-up appointments at 3, 5.5, and 6 months.
Compensation
Incentivized text messages are mentioned, suggesting some form of compensation for checking in on vaping status.
Follow-up
Participants are followed up at 3, 5.5, and 6 months after the intervention.

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NCT06909500

A Digital Intervention (ACT on Vaping App) for Vaping Cessation in Young Adult E-Cigarette Users

Recruiting
NAAges 18–30InterventionalPrevention
Fred Hutchinson Cancer Center
~1,178 participants
Updated 2026-08-26 on ClinicalTrials.gov
What's tested:Smartphone appText MessageSurvey Administration

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Cotinine-confirmed 30-day point prevalence abstinence from all nicotine and tobacco
Measured over At 6 months post-randomization
Nicotine Dependence
Tobacco-Related Carcinoma
1 sites across 1 states
Washington1
  • Jaimee Heffner, PhD · PRINCIPAL_INVESTIGATOR · Fred Hutch/University of Washington Cancer Consortium

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Age 18-30
Current weekly user of e-cigarette product(s) for the last 30 days
Has a smartphone; either an Android (running version 12 or higher) or iPhone (running iOS version 17 or higher, iPhone 11 or more recent)
Experience downloading and using one or more apps on their smartphone
Have a mobile data plan and/or access to WiFi to support the use of the ACT on Vaping app
Has access to text messaging
Has an email address
United States (US) resident, with a US mailing address
Willing to complete all study procedures
Comfortable reading and writing in English

Exclusion

Currently using other tobacco cessation treatments at the time of screening, including pharmacotherapy or behavioral support (note: use of these treatment is allowable during trial participation)
Member of the same household as another research participant
Currently in prison
Google voice number as sole phone number, due to its association with fraudulent study entry attempts
Is ineligible per fraud prevention protocol
Employees/family of investigator or study center
  • Cotinine-confirmed 30-day point prevalence abstinence from all nicotine and tobaccoAt 6 months post-randomization

    Biochemically confirmed 30-day abstinence from all nicotine and tobacco (excluding Food and Drug Administration \[FDA\]-approved pharmacotherapies). Will be assessed in each individual and summarized within each group as a proportion.