Back to search results

ATRIAL-MR Study for Atrial Functional Mitral Regurgitation

This study, called ATRIAL-MR, is looking at how people with atrial functional mitral regurgitation (a type of leaky heart valve) are doing with their usual medical care. It's focused on understanding the outcomes of a procedure called transcatheter edge-to-edge repair, which helps fix the leaky valve. You might be able to join if you are 18 or older, have functional mitral regurgitation, and your heart's pumping ability (left ventricular ejection fraction) is 50% or higher. The main goal is to see how many people experience death from any cause or need to be re-hospitalized for heart failure within 12 months. The study is currently unclear about its recruitment status.

Study design
This is an observational study that plans to include 1000 participants. It is a retrospective registry, meaning it looks back at existing patient information.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants' outcomes will be measured for 12 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06911099

Assessment of Transcatheter Edge-to-Edge Repair in Atrial Functional Mitral Regurgitation (ATRIAL-MR)

Recruiting
Not specifiedAges 18+Observational
University Hospital of Cologne
~1,000 participants
Updated 2025-04-06 on ClinicalTrials.gov

At a glance

Recruiting sites
22 of 22 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Composite of all-cause mortality and heart-failure related rehospitalitzation
Measured over 12 months

Conditions

Atrial Functional Mitral Regurgitation
Mitral Insufficiency

Explore related trials

Functional mitral regurgitation

Where it's being run

22 sites across 8 states
Germany8
Spain5
Italy3
France2
New York1
Canada1
Bavaria1
North Rhine-Westphalia1

Study leadership

  • Christos Iliadis, MD · PRINCIPAL_INVESTIGATOR · Heart Center, Department III of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany

Who to contact

Philipp von Stein, MD
[email protected]
646-321-8145
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

functional mitral regurgitation
left ventricular ejection fraction ≥50%

Exclusion

age under 18 years
known regional wall movement disorders

What this trial measures

  • Composite of all-cause mortality and heart-failure related rehospitalitzation12 months