BioPoly® Partial Resurfacing Knee Implant for Knee Pain and Cartilage Damage

This study is testing the BioPoly® Partial Resurfacing Knee Implant for people with knee pain and cartilage damage. It's for adults aged 30 to 65 whose knee pain hasn't improved with other treatments. Researchers want to see if this implant is safe and works better than standard surgeries like microfracture or debridement. Success in this study means you don't need another knee surgery and your Knee injury and Osteoarthritis Outcome Score (KOOS) improves by at least 10 points. The study is currently unclear on its recruitment status, but plans to enroll 152 participants.

Study design
This is a randomized controlled study comparing the BioPoly® implant to standard surgical care, with 152 planned participants.
What's involved
You would need to comply with all study requirements, including post-operative rehabilitation and follow-up protocols.
Compensation
Not stated in the trial record.
Follow-up
Your progress will be followed for 24 months after the surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06915363

BioPoly® Partial Resurfacing Knee Implant IDE

Recruiting
NAAges 30–65InterventionalTreatment
BioPoly LLC
~152 participants
Updated 2026-07-08 on ClinicalTrials.gov
What's tested:BioPolysurgical standard of care (SSOC)

At a glance

Recruiting sites
4 of 4 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Improvement in the Knee injury and Osteoarthritis Outcome Score (KOOS) to Assess Composite Clinical Success (CCS) effectiveness
Measured over 24 months
+1 more outcome measured
Knee Pain Chronic
Knee Osteoarthritis
Cartilage Damage
Cartilage Defects of the Knee
Cartilage or Osteochondral Defects in the Knee
Cartilage Lesion

NCT06915363

Where you'd take part

This study runs at 4 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Mayo Clinic

    Rochester, Minnesotastudy coordinator listed

    Recruiting

  • OrthoIndy

    Indianapolis, Indianastudy coordinator listed

    Recruiting

  • Washington University Orthopedics

    Chesterfield, Missouristudy coordinator listed

    Recruiting

  • Dupont Hospital

    Fort Wayne, Indianano site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Herb Schwartz, Ph.D. · STUDY_DIRECTOR · BioPoly LLC

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  • Improvement in the Knee injury and Osteoarthritis Outcome Score (KOOS) to Assess Composite Clinical Success (CCS) effectiveness24 months

    An improvement from baseline in the Knee injury and Osteoarthritis Outcome Score (KOOS) total score (scaled 0 to 100) of at least 10 points. If this criteria is met, the subject will be considered as a success relative to the measure of the Clinical Composite Success for effectiveness.

  • Composite Clinical Success (CCS) Safety as Measured by No Secondary Surgical Intenvention24 months

    No secondary surgical intervention (SSI) by 24 months will be considered as a success for the subject relative to the Composite Clinical Success (CCS) for Safety.