NCT06916728
A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Standard of Care (SSOC) Used for the Treatment of Joint Surface Lesions of the Knee
Enrolling by Invitation
Not specifiedAges 21–75ObservationalSmith & Nephew, Inc.
~170 participants
Updated 2026-07-16 on ClinicalTrials.gov
What's tested:Marketed Product - MP01Surgical Standard of Care
At a glance
Recruiting sites
0 of 8 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from Baseline in Overall Knee Injury and Osteoarthritis Outcome Score (KOOS) at 7 Years
Measured over Baseline and 7 years
Conditions
Where it's being run
8 sites across 6 statesItaly2
Serbia2
California1
Belgium1
Israel1
Romania1
Study leadership
- Samantha Andrews · STUDY_CHAIR · Smith & Nephew, Inc.
- Galit Reske · STUDY_CHAIR · Smith & Nephew, Inc.
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
What this trial measures
- Change from Baseline in Overall Knee Injury and Osteoarthritis Outcome Score (KOOS) at 7 YearsBaseline and 7 years
Long-term effectiveness of Marketed Product - MP01 compared to SSOC measured by change in baseline to year 7 in overall KOOS (mean of Pain, Symptoms, Quality of Life (QOL), Function in Daily Living (ADL) and Sports subscales) in subjects treated with Marketed Product - MP01 vs SSOC. Baseline is defined as the pivotal study screening visit. Overall scores are converted to a 0-100 scale, with 0 representing extreme knee problems and 100 representing no knee problems (i.e., a lower score is a worse outcome, and high score is a better outcome).