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NCT06920407

BreatheWell: Train Your Breathing, Relax Your Body, Open Your Mind

Enrolling by Invitation
NAAges 18+InterventionalPrevention
University of California, Los Angeles
~150 participants
Updated 2026-05-13 on ClinicalTrials.gov
What's tested:Breathing training device (Inspiratory Muscle Training)Oura Ring

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Psychological Well-Being
Measured over From enrollment to the completion of the 12-week intervention period, followed by the observational period extending until week 24.
+5 more outcomes measured

Conditions

Healthy

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Healthy VolunteersStress

Where it's being run

1 sites across 1 states
California1

Study leadership

  • Paul Macey, PhD · PRINCIPAL_INVESTIGATOR · Professor

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Age 18 or higher
Stable health for the past 3 months.

Exclusion

IMT contraindications which relate to people who should not raise lung, thoracic, or sinus pressures
Current or recent (\< 3 months) use of cardiovascular or psychotropic medications
Diagnosed psychotic disorders
Current participation in therapy
Recent initiation of mind-body practice
Current major illness or injury
Regular use of personal tracking devices to monitor sleep, heart rate, activity, or related physiological data.

What this trial measures

  • Change in Psychological Well-BeingFrom enrollment to the completion of the 12-week intervention period, followed by the observational period extending until week 24.

    Psychological well-being will be assessed using the NIH Toolbox Psychological Well-Being Scale. This instrument evaluates life satisfaction, positive emotions, and sense of purpose. Higher scores indicate greater psychological well-being. Unit of Measure: Standardized scale score

  • Change in Body AwarenessFrom enrollment to the end of the 12-week intervention period, followed by an observational period through week 24.

    Body awareness will be assessed using the Multidimensional Assessment of Interoceptive Awareness (MAIA), a validated questionnaire examining emotional awareness, body listening, and self-regulation. Higher scores indicate greater interoceptive awareness. Unit of Measure: Questionnaire scale score

  • Change in Heart Rate Variability (HRV)From enrollment to the end of the 12-week intervention period, followed by an observational period through week 24.

    Heart rate variability will be assessed using the Root Mean Square of Successive Differences (RMSSD), reported in milliseconds. RMSSD reflects parasympathetic nervous system activity, with higher values indicating greater physiological relaxation. Unit of Measure: Milliseconds (ms)

  • Change in Inspiratory Muscle StrengthFrom enrollment (first physiology visit) to the end of the 12-week intervention period.

    Inspiratory muscle strength will be measured using the PowerBreathe training device and reported in centimeters of water pressure (cmH₂O), representing the pressure generated during inhalation against resistance. Unit of Measure: cmH₂O

  • Change in Peak Inspiratory Flow RateFrom enrollment (first physiology visit) to the end of the 12-week intervention period.

    Peak inspiratory flow rate will be measured using the PowerBreathe training device and recorded in liters per minute (L/min), indicating the maximum airflow achieved during inhalation. Unit of Measure: Liters per minute (L/min)

  • Change in Inhaled Volume per BreathFrom enrollment (first physiology visit) to the end of the 12-week intervention period.

    Inhaled volume per breath will be assessed using the PowerBreathe training device and measured in milliliters (mL), indicating changes in lung capacity throughout the intervention. Unit of Measure: Milliliters (mL)