COMFORT Trial: Pain Management for Complex Cesarean Deliveries
This study, called the COMFORT Trial, is looking at how well a nerve block called a Transversus Abdominis Plane (TAP) block helps manage pain after complex cesarean deliveries. If you join, you would receive either bupivacaine (a numbing medicine) or a placebo (saltwater) as part of your TAP block during surgery. The researchers want to see if bupivacaine reduces the amount of opioid pain medicine you need after surgery. You may be able to join if you are a woman between 18 and 50 years old and have a history of certain abdominal surgeries or three or more prior cesarean deliveries. The study will measure how much pain medication you request between 24 and 48 hours after surgery. The current status of this study is unclear.
- Study design
- This interventional study plans to enroll 120 women. Participants will be randomly assigned to receive either bupivacaine or a placebo as part of their TAP block.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your pain medication requests will be measured between 24 and 48 hours after surgery.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Pain medication requestedBetween 24 and 48 hours after surgery
Total pain medication requested expressed in morphine milligram equivalents.