Music Intervention with Cognitive Processing Therapy for PTSD

This study is looking at whether adding a special type of music, called Frequency Filtered Music, can make Cognitive Processing Therapy (CPT) more effective for people with Post-Traumatic Stress Disorder (PTSD). CPT is a therapy that helps you understand how traumatic events affect your thoughts and beliefs. Researchers want to see if Frequency Filtered Music helps reduce PTSD symptoms and improve how your body handles stress. They will compare it to regular classical music. To join, you need to be at least 18 years old and have PTSD or similar symptoms, and be able to attend daily in-person therapy sessions. The study will measure PTSD symptom severity for up to 6 months after treatment to see if the intervention is successful. The current status of this study is unclear.

Study design
This interventional study plans to enroll 100 participants who will be randomly assigned to receive either Frequency Filtered Music or Unfiltered Music alongside their Cognitive Processing Therapy.
What's involved
You would attend two weeks of daily in-person therapy sessions at either the Ohio State University or another specified location.
Compensation
Not stated in the trial record.
Follow-up
Your PTSD symptoms will be measured at 1 month, 3 months, and 6 months after completing treatment.

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NCT06925867

A Frequency-Modulated Music Intervention to Enhance Cognitive Processing Therapy (CPT) for PTSD

Recruiting
NAAges 18+InterventionalTreatment
Ohio State University
~100 participants
Updated 2026-02-03 on ClinicalTrials.gov
What's tested:Frequency Filtered MusicUnfiltered MusicCognitive Processing Therapy for PTSD

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
PTSD Symptom Severity (Self Rated)
Measured over 1 month after treatment completion
+2 more outcomes measured
PTSD - Post Traumatic Stress Disorder
2 sites across 1 states
Ohio2

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Eligibility criteria

Inclusion

At least 18 years of age
Meets diagnostic criteria for a) PTSD or b) subthreshold PTSD with hyperarousal (i.e., meets diagnostic threshold for 3 of 4 symptoms, one of which is hyperarousal)
Ability to move between sitting to standing without assistance
Ability to attend two weeks of daily in-person therapy sessions at either the Ohio State University or at the Wright-Patterson Air Force Base (WPAFB) Medical Center

Exclusion

Heart condition (such as cardiac arrhythmia) or pacemaker
An allergy that would prevent wearing adhesive for durations of 2 hours or less
Insufficient English fluency to fully engage in psychotherapy
Use of hearing aids
Current or prior tinnitus (persistent ringing or other noises in ears not caused by an external sound)
Severe traumatic brain injury
An ongoing stressor or condition deemed by the investigators to place the participant at risk for injury or a poor outcome (e.g., undergoing disability evaluation, undergoing a medical board evaluation to be medically discharged from the military, pending negative administrative or legal actions).
Inability to complete the informed consent process due to the acute effects of a medical or psychiatric condition (e.g., intoxication, mania, psychosis)
  • PTSD Symptom Severity (Self Rated)1 month after treatment completion

    PTSD symptom severity will be assessed using the PTSD Checklist for DSM 5 (PCL-5). The scale includes 20 items that rate the severity of each symptom using a 5-point scale, with items summed to provide an overall metric of PTSD symptom severity.

  • PTSD Symptom Severity (Self Rated)3 months after treatment completion

    PTSD symptom severity will be assessed using the PTSD Checklist for DSM 5 (PCL-5). The scale includes 20 items that rate the severity of each symptom using a 5-point scale, with items summed to provide an overall metric of PTSD symptom severity.

  • PTSD Symptom Severity (Self Rated)6 months after treatment completion

    PTSD symptom severity will be assessed using the PTSD Checklist for DSM 5 (PCL-5). The scale includes 20 items that rate the severity of each symptom using a 5-point scale, with items summed to provide an overall metric of PTSD symptom severity.