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Heat Therapy and Mobility in Long COVID Survivors

This study, called "Heat thErapy And mobiLity in COVID-19 Survivors," is looking at new ways to help people aged 50-90 who have long COVID (PASC, or Post-acute sequelae of SARS-CoV-2 infection). Many people with long COVID have ongoing tiredness or difficulty with physical activities. This trial is testing if at-home lower body heat therapy can improve physical abilities and overall health. Some participants will receive heat therapy, others a sham (inactive) treatment, and some will do a walking intervention. We'll measure success by looking at how far you can walk in 6 minutes, your physical performance (Short Physical Performance Battery Test), and the stiffness of your arteries after 8 weeks. We're looking for 99 participants who have had COVID-19 and still have symptoms for at least two months, and who don't have certain other health conditions.

Study design
This is an interventional study with a planned enrollment of 99 participants, comparing different behavioral interventions.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Primary outcomes are measured at 8 weeks after the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06928116

Heat thErapy And mobiLity in COVID-19 Survivors

Recruiting
NAAges 50–90InterventionalTreatment
University of Nebraska
~99 participants
Updated 2026-07-17 on ClinicalTrials.gov
What's tested:Heat therapySham ControlWalking

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
6 min walking distance
Measured over 8 weeks
+2 more outcomes measured

Conditions

Long COVID

Explore related trials

Mobility LimitationPost-Acute Sequelae of COVID-19

Where it's being run

1 sites across 1 states
Nebraska1

Study leadership

  • Gwenael Layec, PhD · PRINCIPAL_INVESTIGATOR · University of Nebraska

Who to contact

Gwenael Layec, PhD
[email protected]
402-554-3779
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Between the ages of 50 and 90 years
Free from orthopedic limitations that would prohibit performing leg exercise
BMI \< 40 kg/m2 and weigh \< 400lbs
Previously contracted Covid-19 and have persistent symptoms such as a fatigue or decline in physical function, for at least 2 months following SARS-CoV-2 infection

Exclusion

Unable to give written informed consent
Women who are pregnant, breastfeeding, or likely to become pregnant within the next 6 months
Women who are taking hormone therapy
Claustrophobia
Orthopedic limitations that would prohibit them from walking
Currently enrolled in an exercise-based or respiratory muscle rehabilitation program.

What this trial measures

  • 6 min walking distance8 weeks

    Distance covered during 6 min of walking

  • Short Physical Performance Battery Test8 weeks

    Test of physical functional capacity

  • Arterial stiffness8 weeks

    Pulse Wave velocity