DUSTS: Dexamethasone for Ureteral Stent Symptoms

This study, called DUSTS, is looking at whether a higher dose of dexamethasone, a steroid, can help reduce pain and urinary symptoms after surgery for kidney stones. During this surgery, a small tube called a ureteral stent is placed. Researchers want to see if giving 20 mg of dexamethasone, compared to the usual 4 mg, improves your quality of life two days after surgery. You may be able to join if you are between 18 and 70 years old, are having a ureteroscopy (a procedure to remove kidney stones) with a stent placed, and can read English. The study is currently recruiting about 70 participants.

Study design
This interventional study will randomly assign participants to receive either 20 mg or 4 mg of dexamethasone. About 70 participants will be enrolled.
What's involved
You will receive dexamethasone during surgery, fill out questionnaires on day 1 and 2 after surgery, complete a medication diary for one week, and have a clinic visit on day 2. You will be in the study for 30 days.
Compensation
Not stated in the trial record.
Follow-up
Your quality of life will be measured two days after surgery, and you will be in the study for a total of 30 days.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06930690

Dexamethasone for Ureteral STent Symptoms (DUSTS)

Recruiting
PHASE1Ages 18–70InterventionalTreatment
The Methodist Hospital Research Institute
~70 participants
Updated 2026-05-29 on ClinicalTrials.gov
What's tested:Dexamethasone Sodium Phosphate Injection 20 mgDexamethasone Sodium Phosphate Injection 4mg

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Global Quality of Life Score of Ureteral Stent Symptom Questionnaire (USSQ)
Measured over Day 2 after surgery
Ureteral Stent-Related Symptom
1 sites across 1 states
Texas1
  • Monica Morgan, MD · PRINCIPAL_INVESTIGATOR · The Methodist Hospital Research Institute

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  • Global Quality of Life Score of Ureteral Stent Symptom Questionnaire (USSQ)Day 2 after surgery

    A 1 to 7 rating scale used to measure survey participants' feeling if they were advised to have another stent inserted, from 1 = delighted to 7 = terrible.